卡替洛尔联合匹多康液体敷料治疗浅表型婴幼儿血管瘤的临床研究  

Clinical Study on Carteolol Combined with Pidokon Liquid Dressing in the Treatment of Superfi cial Infantile Hemangioma

作　　者：丁汉文 陈勇[1] 王倩[1] 王慜 袁斯明 DING Hanwen;CHEN Yong;WANG Qian;WANG Min;YUAN Siming(Department of Burn and Plastic Surgery,Jinling Hospital,Nanjing Medical University,Nanjing 210000,Jiangsu,China)

机构地区：[1]南京医科大学附属金陵医院烧伤整形科,江苏南京210000

出　　处：《中国美容医学》2024年第6期65-68,共4页Chinese Journal of Aesthetic Medicine

基　　金：国家自然科学基金(编号:81272989)。

摘　　要：目的:探讨应用卡替洛尔联合匹多康液体敷料治疗浅表型婴幼儿血管瘤的效果。方法:回顾性分析2016年1月-2021年12月在笔者科室接受卡替洛尔联合匹多康液体敷料外涂治疗的23例浅表型婴幼儿血管瘤患儿的临床资料。治疗方法为每次外敷时间90min,一日3次,持续6~12个月。治疗后将患儿疗效分为三级进行评定:Ⅰ级,治疗无效,需改用其他治疗方法;Ⅱ级,控制瘤体生长;Ⅲ级,促进瘤体消退。结果:23例进行上述治疗的患儿中,Ⅲ级患儿达16例,其中完全消退或仅残留毛细血管扩张的有5例;Ⅱ级3例;Ⅰ级4例。湿疹和溃疡为常见局部不良反应。结论:卡替洛尔联合匹多康液体敷料外用治疗浅表型婴幼儿血管瘤有较好效果。Objective To investigate the therapeutic effect of topical Carteolol combined with pidokon liquid dressing on superficial infantile hemangioma.Methods From January 2016 to December 2021,Carteolol combined with pidokon liquid dressing was given to 23 patients with superficial infantile hemangioma for three times a day for 90 minutes each time.The duration of the treatment was six to twelve months.After treatment,the therapeutic effects were grade as:gradeⅠ(unable to control the growth of the hemangioma),Ⅱ(the growth of the hemangioma was arrested),Ⅲ(hemangioma significantly involuted).Results In the 23 children who underwent these treatments,there were four patients of gradeⅠ,three patients of gradeⅡ,sixteen patients of gradeⅢ.Complete clearance was achieved infive patients.Eczema and ulcer were common local adverse reactions.Conclusion In the treatment of superficial infantile hemangioma during proliferative phase,topical applying of Carteolol combined with pidokon liquid dressing presents good clinical efficacy.

关 键 词：卡替洛尔 婴幼儿血管瘤 匹多康液体敷料 外用 

分 类 号：R729[医药卫生—儿科]