防己黄芪汤应用于腹壁整形术后效果观察  

Observation of the Postoperative Effect of Fangji Huangqi Decoction on Abdominoplasty

作　　者：陈晓芳 韩星 曹于 姬东硕 CHEN Xiaofang;HAN Xing;CAO Yu;JI Dongshuo(Department of Plastic and Reconstructive Surgery,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100016,China;Department of Aesthetic Plastic Surgery,Beijing Hospital of Integrative Traditional Chinese and Western Medicine,Beijing 100039,China)

机构地区：[1]首都医科大学附属北京朝阳医院整形外科,北京100016 [2]北京中西医结合医院美容整形科,北京100039

出　　处：《中国美容医学》2024年第6期97-100,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:评估防己黄芪汤应用于腹壁整形术后早期对皮瓣充血消退、减少早期并发症的作用。方法:选取2019年1月-2022年3月就诊于笔者医院需要进行腹壁整形的就医者37例,随机分为实验组和对照组,根据就医者腹壁松弛程度选择对应术式。实验组术后服用防己黄芪汤28 d,对照组术后予以口服等量无任何药理作用的安慰剂。比较两组术前术后腹部轮廓评分、炎性指标变化及并发症发生情况。结果:与实验组相比,实验组就医者术后2个月及术后6个月腹部轮廓评分明显高于对照组(P<0.05)。术后两组并发症发生率比较差异无统计学意义。术后早期实验组中就医者血管内皮生长因子(Vascular endothelial growth factor,VEGF)、肿瘤坏死因子α(TNF-α)水平明显低于对照组(P<0.05),提示防己黄芪汤可以减轻就医者炎性反应水平,从而提高术后早期恢复效果。结论:防己黄芪汤具有益气祛风、健脾利水的作用,在手术初期尽早进行干预可减轻术后就医者炎性反应,改善术区血瘀水肿的状态,提高术后整体效果。Objective The purpose of this study was to evaluate the postoperative effects of Fangji Huangi Decoction on reducing congestion in skinflaps and early complications after abdominoplasty.Methods Thirty-seven healthy female patients undergoing abdominoplasty were randomly assigned to either an experimental group or a control group.The corresponding surgical procedures were selected based on the degree of abdominal wall laxity for each group.The experimental group received oral administration Fangji Huangqi Decoction orally for 28 days postoperatively,while the control group received an equal amount of placebo with no pharmacological effects.Various parameters including the preoperative and postoperative abdominal scores,changes in inflammatory markers,and occurrence of complications were observed and compared between the two groups.Results Compared to the control group,the patients in the experimental group had significantly higher abdominal scores at 2 months and 6 months postoperatively,with statistical significance(P<0.05).However,there was no significant difference in the incidence of complications between the two groups postoperatively(P>0.05).In the early postoperative period,the levels of VEGF and TNF-ɑin the experimental group were lower than those in the control group,indicating that Fangji Huangqi Decoction can reduce the inflammatory response level in patients,thus improving the early postoperative outcomes.Conclusion Fangqi Huangqi Decoction demonstrated the potential to improve the inner environment.Early intervention with Fangji Huangqi Decoction post-operatively can reduce the inflammatory reaction of patients,improving the state of blood stasis and edema in the operative area,finally improving the overall postoperative results.

关 键 词：防己黄芪汤 腹壁整形术 并发症 血清肿 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]