中医古籍中驻颜处方的内服法及用药规律探析  

Oral administration and medication rule of anti-aging prescriptions in Chinese medical classics

作　　者：万玉凯 杨羽静 邱俊琛 黄云城 秦冬杰 张志辉 刘洋[1] 王颖仪 老膺荣 徐福平 WAN Yukai;YANG Yujing;QIU Junchen;HUANG Yuncheng;QIN Dongjie;ZHANG Zhihui;LIU Yang;WANG Yingyi;LAO Yingrong;XU Fuping(Guangzhou University of Chinese Medicine,Guangzhou 510405,Guangdong,China;The First Affiliated Hospital of Hainan Medical University,Haikou 570102,Hainan,China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510120,Guangdong,China)

机构地区：[1]广州中医药大学,广东广州510405 [2]海南医学院第一附属医院,海南海口570102 [3]广州中医药大学第二附属医院,广东广州510120

出　　处：《湖南中医杂志》2024年第4期32-37,共6页Hunan Journal of Traditional Chinese Medicine

基　　金：广东省科技计划项目(2021B1212100007);广东省广州市科技计划项目(2023A03J0736);广东省中医院颜德馨学术经验传承工作室建设项目(中医二院[2014]89号-6)。

摘　　要：目的:探讨中医古籍中驻颜处方的内服法及用药规律。方法:收集整理中医智库·数字图书馆中具有驻颜功效的中医古籍处方,采用Microsoft Excel 2016软件对筛选出的方剂剂型、辅料、送服介质、送服温度等进行频次统计,归纳总结用药规律。结果:最终纳入112首古籍处方,涉及282味中药。高频中药以温性、甘味的补虚药为主,归经以肾经为主;剂型以丸剂为主;使用辅料总频次为123次,其中蜂蜜、酒、麦芽最为常见;送服介质共21种,总频次达159次,其中频次最高的为酒(82次);送服温度以温服为主。通过聚类分析、关联规则可以得出聚类方3组及药对组合15对。结论:驻颜处方多见以补虚药为主,尤以补肝肾药物相对较多,且以温酒丸剂内服效果较佳。Objective:To investigate the oral administration and medication rule of anti-aging prescriptions in Chinese medical classics.Methods:The prescriptions with anti-aging function in Chinese medical classics were collected from Traditional Chinese Medicine Zhiku Digital Library,and Microsoft Excel 2016 was used for frequency statistics of dosage form of prescriptions,excipients,medium for oral administration,and temperature for oral administration to summarize the medication rules.Results:A total of 112 prescriptions were included,involving 282 traditional Chinese medicine drugs in total.The drugs with a high frequency of use were mostly deficiency-tonifying herbs with a warm nature and a sweet taste,and the drugs mainly entered the kidney meridian.Most prescriptions had a dosage form of pills.The total frequency of use of excipients was 123 times,with honey,wine,and malt as the most common excipients.There were 21 media for oral administration,with a total frequency of 159 times,among which wine had highest frequency of 82 times.Most drugs were taken at a warm temperature.The cluster analysis and the association rule analysis obtained 3 clusters and 15 drug combinations.Conclusion:Deficiency-tonifying herbs are mainly used in anti-aging prescriptions,especially the drugs for tonifying the liver and the kidney,and oral administration of pills with wine at a warm temperature has a relatively good effect.

关 键 词：驻颜处方 中医古籍 数据挖掘 内服法 用药规律 

分 类 号：R242[医药卫生—中医临床基础]