微透析(微灌注)技术在经皮给药制剂中的研究进展  

Progress of microdialysis (dermal open flow microperfusion)in transdermal drug delivery systems

作　　者：汤宏敏 郑丽娥[2] 冯瑞妮 潘宪伟 陈华[2] TANG Hongmin;ZHENG Li′e;FENG Ruini;PAN Xianwei;CHEN Hua(Beijing Hebang Xingye Scientific Instrument Co.,Ltd,Beijing 100073,China;National Institute for Food and Drug Control Beijing 102629,China;Jiangsu Carephar Pharmaceutical Co.,Ltd.Nanjing 210016,China)

机构地区：[1]北京合邦兴业科学仪器有限公司,北京100073 [2]中国食品药品检定研究院,北京102629 [3]江苏柯菲平医药股份有限公司,南京210016

出　　处：《中国药品标准》2024年第2期118-125,共8页Drug Standards of China

摘　　要：通过梳理微透析(微灌注)技术的原理及特性,总结其在经皮给药制剂研究中的应用现状,分析了存在的问题和挑战,对未来发展方向进行展望,并提出相关建议,为该领域的进一步研究提供参考。This paper combed the principle and characteristics of microdialysis(microperfusion)technology,summarized the application status in transdermal drug delivery system and analyzed the problems and challenges.It also outlooked on future development direction and provide relevant suggestions which can contribute to provide reference for further research in this field.

关 键 词：经皮给药制剂 微透析 皮肤开流微灌注 皮肤药代动力学 

分 类 号：R921.2[医药卫生—药学]