消化道早癌智能光学微创诊疗研究现状及展望  

State-of-the-Art and Prospects of Intelligent Optical Minimally Invasive Theranostics for Early Gastrointestinal Cancer

作　　者：刘帅[1] 许连成 董国昭 唐晓英[1] 廖洪恩[2] 范应威 LIU Shuai;XU Liancheng;DONG Guozhao;TANG Xiaoying;LIAO Hongen;FAN Yingwei(School of Medical Technology,Beijing Institute of Technology,Beijing 100081,China;Department of Biomedical Engineering,School of Medicine,Tsinghua University,Beijing 100084,China)

机构地区：[1]北京理工大学医学技术学院,北京100081 [2]清华大学医学院生物医学工程系,北京100084

出　　处：《中国医疗设备》2024年第6期143-155,共13页China Medical Devices

基　　金：国家自然科学基金(82172112,81901907);北京理工大学“朗月计划”(2022LY-22);北京理工大学学术启动计划(XSQD-202123006)。

摘　　要：消化道早癌微创治疗是当前研究热点。手术是目前消化道肿瘤有效的治疗方式,但因手术依赖医生经验、消化道早癌术中智能刻画困难、治疗效应动态监测难等,急需先进的新型设备革新当前的诊疗模式,因此研发智能微创诊疗系统成为需要迫切攻克的关键难题。针对消化道肿瘤等智能诊疗的核心问题,研制智能微创诊疗仪器具有重要的意义,能够为解决当前肿瘤诊疗提供重要的解决方案。本文分别介绍面向消化道早癌的基于光学技术的成像方法、智能精准诊断方案、图像引导手术治疗、机器人辅助智能治疗等方面的研究及临床应用情况,针对这些方面进行讨论和提出未来可能的发展方向,以及指出未来拟研究的介入式智能多模态光学微创诊疗一体化关键问题,以期为从事消化道微创诊疗一体化关键问题研究和智能诊疗仪器研制提供参考建议。Minimally invasive treatment for early gastrointestinal cancer is currently a research hotspot.Surgery is currently an effective treatment method for gastrointestinal tumors.However,due to the dependence of surgery on doctor experience,difficulties in intelligent characterization during early gastrointestinal cancer surgery,and difficulties in dynamic monitoring of treatment effects,advanced new equipment is urgently needed to innovate the current diagnosis and treatment mode.Therefore,the development of intelligent minimally invasive theranostics systems has become an urgent key challenge to overcome.Aiming at the core problems of intelligent diagnosis and treatment such as gastrointestinal tumors,the development of intelligent minimally invasive diagnosis and treatment instruments is of great significance,and can provide important solutions for the current theranostics of tumors.This article introduced the research and clinical applications of optical technology based imaging methods,intelligent precise diagnosis schemes,image guided surgical treatment,robot assisted intelligent treatment,and other aspects for early gastrointestinal cancer.It discussed and proposed possible future development directions in these areas,and pointed out the key issues of integrated invasive intelligent multimodal optical minimally invasive theranostics to be studied in the future,so as to provide reference suggestions for the research on the key issues of minimally invasive diagnosis and treatment integration of gastrointestinal and the development of intelligent diagnosis and treatment instruments.

关 键 词：光学诊疗 激光消融 光学成像 智能医学 微创诊疗 

分 类 号：R197.3[医药卫生—卫生事业管理]