D-异抗坏血酸钠热解碳构建电化学传感器检测黄芩素和木犀草素  

Electrochemical sensor constructed of sodium ascorbate pyrolysis carbon for the determination of baicalein and lignocaine

作　　者：高仪 陈泇冰 刘耀鹏 储婷婷 黄文胜 郑寅 GAO Yi;CHEN Jiabing;LIU Yaopeng;CHU Tingting;HUANG Wensheng;ZHENG Yin(College of Chemical and Environmental Engineering Hubei Minzu University,Enshi 445000,China;Hubei Provincial Key Labortory of Occurrence and Interervention of Rheumatic Diseases,Hubei Minzu University,Enshi 445000,China)

机构地区：[1]湖北民族大学化学与环境工程学院,恩施445000 [2]生物资源保护与湖北省重点实验室,湖北民族大学,恩施445000

出　　处：《分析试验室》2024年第5期633-641,共9页Chinese Journal of Analysis Laboratory

基　　金：国家自然科学基金(22066010);湖北民族大学高水平科研成果校内培育项目(PY22004);湖北民族大学硕士研究生科研创新资助项目(MYK2022030)资助。

摘　　要：以廉价易得的D-异抗坏血酸钠为前驱体,通过一步热解法制备了具有三维互连多孔结构的热解碳材料(SDAIPC),利用扫描电子显微镜(SEM)、透射电子显微镜(TEM)和X射线衍射(XRD)对材料的形貌和结构进行了表征。结果表明,制备的SDAIPC是一类具有高比表面积的碳材料。以SDAIPC为电极修饰材料,构建了用于同时检测黄芩素(BA)和木犀草素(LU)的电化学传感器。通过电化学交流阻抗谱(EIS)和循环伏安法(CV)研究了传感器的电化学性能;采用微分脉冲伏安法(DPV)研究了BA和LU在不同电极上的电化学行为。在优化条件下,SDAIPC修饰电极对BA和LU进行单独检测时的线性范围为0~8.0μmol/L,检出限(LOD)分别为1.39×10^(-9)mol/L和3.02×10^(-10)mol/L;对BA和LU进行同时检测时的线性范围为0.05~2.0μmol/L,LOD分别为3.76×10^(-9)mol/L和3.78×10^(-10)mol/L。该电化学传感器已成功用于BA和LU的实际样品检测。Pyrolytic carbon materials with three-dimensional interconnected porous structures(SDAIPC)were prepared by one-step pyrolysis using inexpensive and readily available sodium D-isoascorbate as a precursor.The morphology and structure of the material were characterized using scanning electron microscopy(SEM),transmission electron microscopy(TEM)and X-ray diffraction(XRD).The results showed that the prepared SDAIPC was a class of carbon materials with high specific surface area.An electrochemical sensor for the simultaneous detection of baicalein(BA)and lignocaine(LU)was constructed using SDAIPC as the electrode modification material.The electrochemical performance of the sensor was investigated by electrochemical impedance spectroscopy(EIS)and cyclic voltammetry(CV),and the electrochemical behavior of BA and LU at different electrodes was studied by differential pulse voltammetry(DPV).Under the optimized conditions,the linear detection ranges of SDAIPC-modified electrode for BA and LU were 0-8.0μmol/L,and the limits of detection(LODs)were 1.39×10^(-9)mol/L and 3.02×10^(-10)mol/L,respectively.The linear detection range for the simultaneous detection of BA and LU was 0.05-2.0μmol/L,and the LODs were 3.76×10^(-9)mol/L and 3.78×10^(-10)mol/L,respectively.The electrochemical sensor could be used for the detection of BA and LU in real samples.

关 键 词：多孔碳材料 电化学传感器 黄芩素 木犀草素 

分 类 号：O657.1[理学—分析化学]