MR动态增强扫描减影技术评估肝癌肝动脉栓塞化疗和射频消融术疗效价值研究  

MR Dynamic Enhanced Scanning Subtraction Technique to Evaluate the Efficacy of Hepatic Arterial Embolization Chemotherapy and Radiofrequency Ablation for Hepatocellular Carcinoma

作　　者：王博生[1] 李立超 邱立燕 WANG Bo-sheng;LI Li-chao;QIU Li-yan(Imaging Department,Xinyi People's Hospital,Guangdong 525300,China)

机构地区：[1]广东省信宜市人民医院影像科,广东525300

出　　处：《影像技术》2024年第3期11-15,24,共6页Image Technology

基　　金：茂名市科技计划项目(210401094550132)。

摘　　要：目的:探讨MR动态增强扫描减影技术评估肝癌肝动脉栓塞化疗(TACE)和射频消融术(RFA)疗效价值。方法:选取2020年12月-2023年11月于我院进行治疗的40例肝癌患者,依据治疗方式的不同分为观察组与对照组,每组各20例。对照组患者和观察组患者均进行MR检查,对照组患者行TACE治疗方法,观察组患者行RFA治疗方法,对比两组患者的临床疗效、不良反应发生情况、肿瘤灭活率、肝功能以及AFP水平。结果:观察组的总有效率为100.00%,对照组的总有效率为75.00%,经过对比,有显著性差异(P<0.05);对照组不良反应发生率为30.00%,观察组不良反应发生率为5.00%,经过对比,有显著性差异(P<0.05);观察组的肿瘤灭活率为92.86%,对照组的肿瘤灭活率为78.95%,经过对比,有显著性差异(P<0.05);治疗之后,两组患者的ALT和AST均高于治疗之前,观察组显而易见低于对照组,AFP水平低于治疗之前,并且观察组显而易见低于对照组,有显著性差异(P<0.05)。结论:对使用MR动态增强扫描减影技术来进行评估的肝癌患者运用RFA进行治疗,能够显著提高患者的临床治疗效果、降低不良反应发生率、提高肿瘤灭活的几率,以及能够明显改善患者肝功能和提高患者的生活质量与水平,值得在临床进行推广。Objective:To discuss the efficacy of MR dynamic enhanced scanning subtraction technique in hepatic transcatheter arterial chemoembolization(TACE)and radio frequency ablation(RFA)for hepatocellular carcinoma.Methods:40 patients with liver cancer treated in our hospital from December 2020 to November 2023 were selected and divided into observation group and control group according to different treatment ways,with 20 cases in each group.Patients in the control group and observation group were underwent to MR examination,and patients in the control group were required to undergo TACE treatment,and patients in the observation group were required to undergo RFA treatment.The clinical efficacy,occurrence of adverse reactions,tumor inactivation rate,liver function and AFP level of the two groups were compared.Results:The total effective rate was 100.00%in the observation group and 75.00%in the control group,and the difference was significant(P<0.05).The incidence of adverse reactions was 30.00%in control group and 5.00%in observation group,and there was a significant difference(P<0.05).The tumor inactivation rate was 92.86%in the observation group and 78.95%in the control group,and the difference was significant(P<0.05).After treatment,ALT and AST in both groups were higher than before treatment,the observation group was significantly lower than the control group,AFP level was significantly lower than before treatment,and the observation group was significantly lower than the control group,with significant differences(P<0.05).Conclusion:The application of RFA in the treatment of liver cancer patients evaluated by MR dynamic enhanced scanning subtraction technology can significantly boost the clinical therapeutic affect of patients,decrease the incidence of adverse reactions,increase the probability of tumor inactivation,and importantly boost the liver function and the quality and level of life of patients.It is worth promoting in clinical practice.

关 键 词：MR动态增强扫描减影技术 肝癌 肝动脉栓塞化疗 射频消融术 

分 类 号：R445.2[医药卫生—影像医学与核医学]