钆塞酸二钠增强MRI在评估肝功能的研究进展  

Research progress of Gadoxetate disodium-enhanced MRI in the evaluation of liver function

作　　者：蒋启红 任勇军[2] Jiang Qihong;Ren Yongjun(Department of Radiology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China;Department of Liver Surgery,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]川北医学院附属医院放射科,四川南充637000 [2]川北医学院附属医院肝胆外科,四川南充637000

出　　处：《中华消化病与影像杂志（电子版）》2024年第2期183-187,共5页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

基　　金：川北医学院附属医院科研发展计划项目(2021ZD015)。

摘　　要：钆塞酸二钠(Gd-EOB-DTPA)是一种肝脏特异性MRI对比剂。近年来,国内外大量研究显示Gd-EOB-DTPA增强MRI在肝功能评估方面具有极大优势,不仅能准确地评估慢性肝病的肝功能,而且还可以用于肝切除术后肝衰竭预测等。本文系统阐述了Gd-EOB-DTPA增强MRI在肝脏弥漫性病变,如非酒精性脂肪性肝病、肝纤维化、肝硬化及肝脏部分切除患者残余肝功能的术前评估等方面的应用现状并进行了展望。Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(Gd-EOB-DTPA)is a liver-specific MRI contrast agent.In recent years,a large number of studies at home and abroad have shown that Gd-EOB-DTPA enhanced MRI has great advantages in liver function assessment,which can not only accurately assess liver function in chronic liver diseases,but also be used to predict liver failure after liver resection.The review systematically describes the application status of Gd-EOB-DTPA-enhanced MRI in the diffuse lesions of the liver,such as nonalcoholic fatty liver diseases,liver fibrosis,cirrhosis and preoperative evaluation of residual liver function in patients with partial liver resection,and forecasts the future of Gd-EOB-DTPA.

关 键 词：磁共振成像 钆塞酸二钠 肝功能 肝脏弥漫性病变 肝切除术后肝衰竭 

分 类 号：R445.2[医药卫生—影像医学与核医学] R575[医药卫生—诊断学]