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作 者:Kristian Rivera Dolors Viles Marta Zielonka Carlos Izurieta Tania Ramírez Martínez Diego Menéndez
出 处:《Journal of Intensive Medicine》2024年第2期261-264,共4页重症医学(英文)
摘 要:Introduction The Gram-positive bacterium,Streptococcus pneumoniae(S.pneumoniae),often colonizes the nasopharynx;however,it is one of the major microorganisms that cause pneumonia and meningitis.[[1],[2],[3]]It presents several virulence factors,such as surface proteins and enzymes,pneumolysin toxin,and a polysaccharide capsule,which is mainly responsible for the immune response;the capsule also facilitates classification of the bacterium into several serotypes.[1,2]In vulnerable individuals,the bacterium may lead to the development of invasive pneumococcal disease(IPD),which is defined as an infection of normally sterile locations.
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