2023年江苏省猴痘病例临床和流行病学特征分析  

Clinical and epidemiological characteristics of mpox cases in Jiangsu province in 2023

作　　者：居豪 王笑辰 梁姝怡 张楠 胡洋 刘慧 朱小娟[4] 赵康辰[4] 葛以跃[4] 李瑞云 胡建利[1] Ju Hao;Wang Xiaochen;Liang Shuyi;Zhang Nan;Hu Yang;Liu Hui;Zhu Xiaojuan;Zhao Kangchen;Ge Yiyue;Li Ruiyun;Hu Jianli(Institute for the Prevention and Control of Acute Infectious Diseases,Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,China;Institute for the Prevention and Control of Acute Infectious Diseases,Nanjing Center for Disease Control and Prevention,Nanjing 210003,China;Department of Infectious Disease Prevention and Control,Suzhou Center for Disease Control and Prevention,Suzhou 215004,China;Institute of Pathogenic Microorganisms,Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,China;School of Public Health,Nanjing Medical University,Nanjing 211166,China)

机构地区：[1]江苏省疾病预防控制中心急性传染病预防控制所,南京210009 [2]南京市疾病预防控制中心急性传染病预防控制所,210003 [3]苏州市疾病预防控制中心传染病预防控制科,215004 [4]江苏省疾病预防控制中心病原微生物研究所,210009 [5]南京医科大学公共卫生学院,211166

出　　处：《国际病毒学杂志》2024年第2期109-113,共5页International Journal of Virology

基　　金：江苏省流行病学重点学科(ZDXK202250);2023年江苏省卫健委定向委托研究重点项目(DX202302)。

摘　　要：目的描述江苏省猴痘的临床和流行病学特征,为疫情防控提供经验。方法使用中国疾病预防控制信息系统和流行病学调查信息系统等的数据,采用Excel 2016软件进行整理和分析数据并绘制发病与报告时间分布图,分析江苏省2023年猴痘的临床和流行病学特征。结果江苏省2023年确诊的120例猴痘病例以散发为主,集中在7~9月,潜伏期为8.0(5.0,11.0)d,主要通过男男性行为传播。患者主要特征为男男性行为者(95.0%)、青壮年(21~45岁,占95.0%)、未婚(68.3%)和无业(49.2%),部分患有艾滋病(46.7%)和梅毒(23.3%)等性传播疾病。临床症状以皮损(91.7%)、发热(60.8%)、淋巴结肿大(37.5%)和头痛(22.5%)为主。病例主要通过主动就诊(90.8%)被发现,发病至就诊和发病至诊断的中位间隔时间分别为2.5 d和7.0 d。结论应继续加强猴痘监测,同时针对男男性行为人群等高危人群加强健康教育。Objective To describe the clinical and epidemiological characteristics of mpox cases in Jiangsu province,so as to provide experience for prevention and control of the epidemics.Methods The clinical and epidemiological data of mpox in Jiangsu Province in 2023 from the China Information System for Disease Control and Prevention and the Epidemiological Investigation Information System were sorted and analyzed,and the time distribution map of incidence and time of reporting were drawn by Excel 2016.Thus the epidemiological and clinical characteristics of mpox in 2023 Jiangsu province were analyzed.Results The 120 mpox cases confirmed in 2023 Jiangsu province were predominantly sporadic cases.These cases were mainly reported from July to September,and the incubation period was 8.0(5.0,11.0)days.The main transmission route was male-male sexual behavior.The major characters of the patients were MSM(95.0%),young adults(21-45 years old,95.0%),unmarried(68.3%)and unemployed(49.2%).Some patients suffered from sexually transmitted diseases such as AIDS(46.7%)and syphilis(23.3%).Main clinical symptoms included skin lesions(91.7%),fever(60.8%),lymph node enlargement(37.5%)and headache(22.5%).The cases were detected mainly by voluntary treatment(90.8%).The median interval from disease onset to medical treatment and the median interval from onset to diagnosis were 2.5 days and 7.0 days,respectively.Conclusions Mpox surveillance should be continuously strengthened,along with health education for MSM and other high-risk groups.

关 键 词：猴痘 流行病学特征 临床特征 男男性行为人群 

分 类 号：R511[医药卫生—内科学] R181.3[医药卫生—临床医学]