P(DM-co-HEMA)水凝胶电化学传感器的构建及其性能研究  

Study on Construction and Properties of P(DM-co-HEMA) Hydrogel Electrochemical Sensors

作　　者：许利剑 邬俊晖 雷清 周日阳 周佳慧 唐曾民 杨平平 XU Lijian;WU Junhui;LEI Qing;ZHOU Riyang;ZHOU Jiahui;TANG Zengmin;YANG Pingping(College of Life Science and Chemistry,Hunan University of Technology,Zhuzhou Hunan 412007,China)

机构地区：[1]湖南工业大学生命科学与化学学院,湖南株洲412007

出　　处：《湖南工业大学学报》2024年第5期47-54,共8页Journal of Hunan University of Technology

基　　金：国家自然科学基金资助项目(52374387)。

摘　　要：以二甲基二烯丙基氯化铵(DM)为主要成分用以提供阳离子基团、甲基丙烯酸羟乙酯(HEMA)和N,N-亚甲基双丙烯酰胺(MBA)为辅助结构单体,制备出聚电解质P(DM-co-HEMA)水凝胶薄膜。在水系环境中,DM为水凝胶提供了良好的抗溶胀性、水解稳定性以及导电性。利用该水凝胶薄膜修饰玻碳电极(GCE),构建了多巴胺(DA)电化学传感器(P(DM-co-HEMA)/GCE)。性能检测结果表明,制备的P(DM-co-HEMA)/GCE对DA有较好的电化学响应。在0.1~0.4 mmol/L和0.4~2.9 mmol/L的DA浓度范围内,氧化峰电流与还原峰电流相应值随DA浓度的增大呈线性增加,相应的检出限为7.41μmol/L(信噪比为3);与裸GCE相比,P(DM-co-HEMA)/GCE具有更好的稳定性和抗干扰性。With dimethyldiallylammonium chloride(DM)as the main component to provide the cationic groups,and with hydroxyethyl methacrylate(HEMA)and N,N-methylenebisacrylamide(MBA)as the auxiliary structural monomers,polyelectrolyte hydrogel film P(DM-co-HEMA)can be successfully prepared.DM provids the hydrogel with good anti-swelling properties,hydrolysis stability and conductivity in an aquatic environment.A dopamine(DA)electrochemical sensor(P(DM-co-HEMA)/GCE)can be constructed by using the hydrogel film modified glassy carbon electrode(GCE).The performance test results show that the prepared P(DM-co-HEMA)/GCE exhibits a good electrochemical response to DA.Within the concentration range of 0.1~0.4 mmol/L and 0.4~2.9 mmol/L of DA,the corresponding values of oxidation peak current and reduction peak current increase linearly with the concentration of DA,with a detection limit of 7.41μmol/L(signal-to-noise ratio of 3),which indicates that compared with bare GCE,P(DM-co-HEMA)/GCE is characterized with a better stability and anti-interference property.

关 键 词：聚电解质水凝胶 抗溶胀性 多巴胺 电化学传感器 

分 类 号：TP212.2[自动化与计算机技术—检测技术与自动化装置]