气象因素和环境因素对慢阻肺急性发病重要性差异研究  

Study on the Difference in the Importance of Meteorological and Environmental Factors on the Acute Onset of Chronic Obstructive Pulmonary Disease

作　　者：黄伟 谭宏宇 方量 HUANG Wei;TAN Hongyu;FANG Liang(Department of Emergency Medicine,Liuzhou Workers′Hospital,Liuzhou,Guangxi Zhuang Autonomous Region,545005 China)

机构地区：[1]柳州市工人医院急诊医学科,广西柳州545005

出　　处：《系统医学》2024年第8期29-31,共3页Systems Medicine

基　　金：自治区卫生健康委自筹经费科研课题(Z-B20231382)。

摘　　要：目的探究气象因素和环境因素对慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,COPD)急性发病重要性的差异。方法选取柳州市工人医院于2021年1月—2023年12月收治的COPD急性发病患者的3460例临床资料以及同期柳州市气象资料和空气质量日报资料为研究对象。对各要素与COPD急性发病就诊数进行Spearman相关分析和多元逐步回归分析,建立COPD预测模型并分析其拟合效果。结果COPD急性发病就诊数与平均气温及平均相对湿度呈负相关(r=-0.539、-0.589,P均<0.05),与SO_(2)及PM2.5呈正相关(r=0.613、0.632,P均<0.05);多元回归分析显示,日温差、相对湿度及PM2.5对COPD急性发病就诊数的影响显著(P均<0.05)。结论日温差、相对湿度及PM2.5对COPD急性发病的影响显著。Objective To investigate the differences in the importance of meteorological and environmental factors on the acute onset of chronic obstructive pulmonary disease(COPD).Methods The clinical data of 3460 patients with acute onset of COPD admitted to Liuzhou Workers′Hospital from January 2021 to December 2023,as well as the meteorological data and air quality daily report data of Liuzhou City during the same period were selected as the research objects.Spearman correlation analysis and multiple stepwise regression analysis were performed on each factor and the number of acute COPD visits,and a COPD prediction model was established and its fitting effect was analyzed.Results The number of acute COPD patients was negatively correlated with average temperature and average relative humidity(r=-0.539,-0.589,both P<0.05),and positively correlated with SO_(2) and PM2.5(r=0.613,0.632,both P<0.05).Multiple regression analysis showed that daily temperature difference,relative humidity and PM2.5 had significant effects on the number of patients with acute COPD(all P<0.05).Conclusion The effects of daily temperature difference,relative humidity and PM2.5 on the acute onset of COPD are significant and should be emphasized.

关 键 词：气象 环境 慢阻肺 急性发病 重要性 差异 

分 类 号：R563.9[医药卫生—呼吸系统]