从中医谈脑-肠轴与腹泻型肠易激综合征的研究进展  

Research progress of brain-gut axis and diarrhea type irritable bowel syndrome from traditional Chinese medicine

作　　者：段勇君 黄学宽[1] 刘西洋 陈晨 刘韵涵 DUAN Yongjun;HUANG Xuekuan;LIU Xiyang;CHEN Chen;LIU Yunhan(College of Traditional Chinese Medicine,Chongqing Medical University,Chongqing 400016,China;Department of Spleen and Stomach Diseases,Traditional Chinese Medicine Hospital.Dianjiang.Chongqing,Chongqing 408300,China)

机构地区：[1]重庆医科大学中医药学院,重庆400016 [2]重庆市垫江县中医院脾胃病科,重庆408300

出　　处：《中国医药科学》2024年第9期36-39,60,共5页China Medicine And Pharmacy

基　　金：重庆市卫生健康委中医药科研项目(2023WSJK151)。

摘　　要：肠易激综合征(IBS)是常见的功能性肠病,其症状反复出现,受情绪压力和生活方式影响较大,与中医肝郁脾虚型,情志不舒诱发腹痛、泄泻相似。脑肠轴对中枢神经系统的感觉和调节异常都可恶化其感知和反射反应,导致内脏感觉高敏状态及胃肠道运动功能的失常。近年来中医治疗腹泻型肠易激综合征(IBS-D)取得良好临床成效,本文通过查阅临床资料和相关文献,从脑-肠轴入手探讨中医治疗IBS-D的临床效果及研究进展,为其治疗提供进一步理论依据。Irritable bowel syndrome(IBS)is a common functional bowel disease,and its symptoms appear repeatedly,which is greatly influenced by emotional stress and lifestyle.It is similar to abdominal pain and diarrhea caused by liver depression and spleen deficiency in traditional Chinese medicine.Abnormal sensation and regulation of the brain-gut axis on the central nervous system can worsen its perception and reflex response,leading to visceral hypersensitivity and dysfunction of gastrointestinal motility.In recent years,traditional Chinese medicine has achieved good clinical results in treating diarrhea type irritable bowel syndrome(IBS-D).By consulting clinical data and related literature,the authors discuss the clinical efficacy and research progress of traditional Chinese medicine in treating IBS-D from the brain-intestine axis in this paper,and provide further theoretical basis for its treatment.

关 键 词：脑-肠轴 腹泻型肠易激综合征 内脏高敏感 胃肠动力异常 中医药 肝郁脾虚 

分 类 号：R259[医药卫生—中西医结合]