巨气管支气管症临床特点分析  

Analysis of clinical characteristics of four cases of tracheobronchomegaly

作　　者：吴艳军[1] 林芳[1] 于刚刚[1] 徐波[1] 姚志刚[1] WU Yanjun;LIN Fang;YU Ganggang;XU Bo;YAO Zhigang(Department of Respiratory,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院慢性阻塞性肺疾病及呼吸介入治疗,100050

出　　处：《心肺血管病杂志》2024年第5期464-468,共5页Journal of Cardiovascular and Pulmonary Diseases

基　　金：国自然青年科学基金项目(82000042);北京市临床重点专科建设项目(2020-2022);北京市通州区科技计划项目(KJ2023CX018)。

摘　　要：目的:分析巨气管支气管症(tracheobronchomegaly,TBM)患者临床特点,以期提高临床医师对该疾病诊疗认识。方法:回顾性收集首都医科大学附属北京友谊医院呼吸内科近5年诊断巨气管支气管症患者临床资料,分析其基本情况、临床症状及体征、影像等临床资料。结果:共收集4例患者,临床症状主要为咳嗽、咳痰及喘憋。男女各2例,最小年龄65岁,最大90岁,女性患者无吸烟史,2例男性患者均有吸烟,均有不同程度的气管扩张,2例患者合并耐药的铜绿假单胞菌感染,1例患者合并结核感染,气管插管1例,死亡1例。结论:巨气管支气管症常合并支气管扩张,可合并耐药菌感染,对症治疗尤其是控制感染尤为重要,高龄患者预后差,气道管理复杂,应予以重视。Objective:To analyze the clinical characteristics of patients with tracheobronchomegaly,in order to improve clinical physicians'understanding of the diagnosis and treatment of this disease.Methods:Retrospective collection of clinical data from patients diagnosed with tracheobronchomegaly disease in the respiratory department of Beijing Friendship Hospital,Capital Medical University over the past 5 years,analysis of their basic conditions clinical symptoms and signs,imaging examination and other clinical data.Results:A total of 4 patients were collected,and their clinical symptoms were mainly cough,sputum production,and wheezing.Two patients were male and the other two patients were female,with a minimum age of 65 years and a maximum age of 90 years.Two female patients had no smoking history,while two male patients were both smokers,and all patients had different degrees of bronchiectasis.2 patients were infected with drug-resistant pseudomonas aeruginosa,1 patient was infected with tuberculosis,1 patient was intubated,and 1 patient died.Conclusions:Tracheobronchomegaly often accompanies bronchiectasis and can be accompanied by drug-resistant bacterial infections.Symptomatic treatment,especially infection control,is particularly important.The prognosis of elderly patients is poor,and airway management is complicated,which should be taken seriously.

关 键 词：巨气管 莫-昆综合征 支气管扩张 

分 类 号：R54[医药卫生—心血管疾病]