SWI对中枢神经系统表面铁质沉积症的诊断价值  

作　　者：俞金娜[1] 邱勇钢[1] 董飞[2] 何聪[1] 徐宏伟[1] 

机构地区：[1]浙江省绍兴第二医院医共体总院,312000 [2]浙江大学附属第二医院,310009

出　　处：《浙江临床医学》2024年第5期744-746,共3页Zhejiang Clinical Medical Journal

基　　金：浙江省绍兴市柯桥区攻关科技计划项目(2017KZ026)。

摘　　要：目的探讨磁敏感加权成像(SWI)对中枢神经系统表面铁质沉积症(SSCNS)的诊断价值。方法选取2015年3月至2021年6月本院行磁共振T2WI、DWI及SWI序列扫描的SSCNS患者43例,比较不同序列对SSCNS及其两种亚型的病灶检出率差异。结果43例SSCNS患者共发现264个分区病灶,其中29例cSS型共计79个分区病灶,14例iSS型共计185个分区病灶。T2WI、DWI、SWI对病灶总体检出率分别为47.7%、60.6%和100.0%,其中对cSS型的病灶检出率分别为39.2%、50.6%、100.0%,对iSS型的病灶检出率分别为51.4%、64.9%、100.0%。DWI与T2WI对cSS病灶检出率差异无统计学意义(P>0.05),对iSS及SSCNS总的病灶检出率差异有统计学意义(P<0.05),SWI与T2WI、DWI对病灶总体和各亚型的检出率差异均有统计学意义(P<0.05)。结论SWI对SSCNS病灶的检出率明显优于T2WI和DWI,有利于早期全面评估SSCNS病情,可将SWI作为SSCNS诊断的常规检查序列。Objective To explore the value of magnetic susceptibility-weighted imaging(SWI)in the diagnosis of superficial siderosis of the central nervous system(SSCNS).Methods 43 cases of SSCNS(including 29 cases of cSS and 14 cases of iSS)who received routine T2WI,DWI and SWI were collected to analyze the MRI performance,and compare the statistical differences of detection rate of lesions on SWI,T2WI and DWI sequences of two subtypes of cSS and iSS.Results For the 43 cases of SSCNS,the all number of lesions was 264,including 29 cases of cSS with 79 lesions and 14 cases of iSS with 185 lesions.The detection rate of T2WI,DWI and SWI was 47.7%,60.6%and 100.0%.The detection rate of cSS lesions was 39.2%,50.6%and 100.0%,and the detection rate of iSS lesions was 51.4%,64.9%and 100.0%.There was no significant difference between DWI and T2WI in the detection rate of cSS(P>0.05),there was significant difference in the detection rate of iSS and SSCNS(P<0.05).There were statistically significant differences between SWI and the other two sequences in the detection rate of SSCNS and two subtypes(P<0.05).Conclusion SWI is more senstive to diagnosis SSCNS than T2WI and DWI,and it is helpful for the early and comprehensive evaluation of iron deposition and distribution range,and SWI should be used as a routine examination sequence for diagnose of SSCNS.

关 键 词：表面铁质沉积症 蛛网膜下腔出血 磁敏感成像 T2WI 

分 类 号：R445.2[医药卫生—影像医学与核医学] R741[医药卫生—诊断学]