红藤败酱二丹汤联合微波治疗湿热瘀结证盆腔炎性疾病后遗症患者的临床疗效观察  

Clinical Efficacy of Hongteng Baijiang Erdan Decoction Combined with Microwave Therapy in the Treatment of Sequela of Pelvic Inflammatory Disease with Dampness-Heat and Stasis Accumulation

作　　者：刘艳芹 刘金秀 秦伟杰 杜惠兰 LIU Yan-qin;LIU Jin-xiu;QIN Wei-jie;DU Hui-lan(Qian′an City Hospital of Traditional Chinese Medicine,Qian′an Hebei 064400;Hebei University of Chinese Medicine,Shijiazhuang Hebei 050299)

机构地区：[1]迁安市中医医院,河北迁安064400 [2]河北中医药大学,河北石家庄050299

出　　处：《世界中西医结合杂志》2024年第5期982-986,992,共6页World Journal of Integrated Traditional and Western Medicine

基　　金：河北省中医药管理局科研计划(2019209)。

摘　　要：目的 观察红藤败酱二丹汤联合微波治疗湿热瘀结证型盆腔炎性疾病后遗症(Sequelae of pelvic inflammatory disease,SPID)的临床疗效。方法 选取2020年1月—2023年3月期间迁安市中医院妇科住院部及妇科门诊收治的湿热瘀结证型SPID患者98例作为研究对象,按随机数字表法分为对照组和治疗组,每组各49例。对照组给予阿奇霉素片治疗,治疗组给予红藤败酱二丹汤口服联合微波治疗,两组患者均连续治疗14 d为1个疗程。观察比较两组患者治疗总有效率以及随访三个月后复发情况,治疗前后血清炎症指标[白细胞介素-6(Interleukin-6,IL-6)、肿瘤坏死因子α(Tumor necrosis factor-α,TNF-α)、C反应蛋白(C-reactive protein,CRP)]、血液流变学指标(高切全血黏度、低切全血黏度、血浆黏度)及湿热瘀结证中医证候评分。结果 治疗后治疗组总有效率95.83%(46/48)明显高于对照组80.85%(38/47),且治疗组复发率4.17%(2/48)明显低于对照组17.02%(8/47),差异有统计学意义(P<0.05)。治疗后两组患者血清CRP、IL-6、TNF-α指标均较治疗前降低,差异有统计学意义(P<0.05);且治疗组血清CRP、IL-6、TNF-α指标均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者全血高切黏度、全血低切黏度、血浆黏度指标均较治疗前降低,差异有统计学意义(P<0.05);且治疗组全血高切黏度、全血低切黏度、血浆黏度指标均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者带下异常、月经异常、腰骶疼痛、下腹刺痛或胀痛、小便黄赤、大便干燥评分均较治疗前明显降低,差异有统计学意义(P<0.05);且治疗组带下异常、月经异常、腰骶疼痛、下腹刺痛或胀痛、小便黄赤、大便干燥评分均明显低于对照组,差异有统计学意义(P<0.05)。结论 红藤败酱二丹汤联合微波治疗湿热瘀结证型盆腔炎性疾病后遗症疗效优于单纯的阿奇霉素治疗,且能�Objective To evaluate the clinical efficacy of Hongteng Baijiang Erdan Decoction combined with microwave therapy for treating the sequelae of pelvic inflammatory disease(SPID)characterized by dampness-heat and stasis accumulation.Methods A total of 98 SPID patients with dampness-heat and stasis accumulation admitted to the gynecological inpatient and outpatient clinics of Qian′an City Hospital of Traditional Chinese Medicine from January 2020 to March 2023 were selected.They were divided into a control group and a treatment group by random number table,with 49 in each group.The control group received azithromycin tablets,while the treatment group received oral administration of Hongteng Baijiang Erdan Decoction combined with microwave therapy.Both groups were treated continuously for 14 days as one course of treatment.The total effective rate and recurrence rate at a three-month follow-up were observed and compared alongside serum inflammatory markers[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)],hemorheological parameters(high-shear whole blood viscosity,low-shear whole blood viscosity,plasma viscosity),and TCM syndrome(dampness-heat and stasis accumulation)scores before and after treatment.Results The total effective rate of the treatment group was 95.83%(46/48),higher than the 80.85%(38/47)of the control group,and the recurrence rate of the treatment group at 4.17%(2/48)was lower than the control group at 17.02%(8/47)(P<0.05).After treatment,both groups demonstrated reductions in serum CRP,IL-6,and TNF-α compared with the conditions before treatment,with the treatment group showing lower levels than the control group(P<0.05).Similarly,all hemorheological indices measured were decreased after treatment in both groups(P<0.05),with the treatment group having greater reductions(P<0.05).Symptom scores related to abnormal vaginal discharge,menstrual disturbances,lumbosacral pain,lower abdominal stabbing or distension,yellowish-red urine,and dry stool were all reduced following trea

关 键 词：盆腔炎性疾病后遗症 红藤败酱二丹汤 微波治疗 湿热瘀结证型 

分 类 号：R711.33[医药卫生—妇产科学]