西药治疗中的合理用药策略及其对患者疗效的影响分析  

Analysis of rational drug use strategy in Western medicine treatment and its influence on patient outcomes

作　　者：胡晓珍 王锐 丁相梅 HU Xiao-zhen;WANG Rui;DING Xiang-mei(Yinan County Qingtuo Center Health Center,Linyi 276300,China)

机构地区：[1]山东省沂南县青驼中心卫生院,276300 [2]山东省临沂市人民医院病案管理科,276300

出　　处：《中国现代药物应用》2024年第10期148-152,共5页Chinese Journal of Modern Drug Application

摘　　要：目的分析西药治疗中合理用药策略与常规用药策略对患者疗效的影响。方法选取2022年1~6月在本院呼吸内科、消化内科、泌尿内科或心内科住院且实施常规用药策略的68例患者作为对照组,2022年7~12月在本院呼吸内科、消化内科、泌尿内科或心内科住院且实施合理用药策略的68例患者作为观察组。对比两组患者病情缓解情况、不良反应发生情况、生活质量、用药依从性。结果观察组的总缓解率94.12%显著高于对照组的60.29%,差异具有统计学意义(P<0.05)。观察组不良反应发生率5.88%显著低于对照组的35.29%,差异具有统计学意义(P<0.05)。观察组生理功能、生理角色、身体疼痛、总体健康、精神健康、社交功能、精神角色、健康变化评分分别为(87.11±2.92)、(89.35±3.11)、(85.94±3.94)、(90.12±2.82)、(89.90±2.53)、(91.73±3.55)、(88.37±3.12)、(88.03±2.54)分,均显著高于对照组的(74.26±3.27)、(71.46±3.56)、(71.09±4.64)、(72.58±4.29)、(72.31±3.79)、(75.98±3.42)、(73.30±3.68)、(72.14±4.13)分,差异具有统计学意义(P<0.05)。观察组的总依从率94.12%高于对照组的66.18%,差异具有统计学意义(P<0.05)。结论与常规用药策略相比,西药治疗中合理用药策略在提高患者病情缓解率、降低不良反应发生率、改善生活质量和提高用药依从性方面具有显著优势。Objective To analyze the rational drug use strategy in Western medicine treatment and its influence on patient outcomes.Methods 68 patients who were hospitalized in the Department of Respiratory Medicine,Department of Gastroenterology,Department of Urology or Department of Cardiology of our hospital from January to June 2022 and implemented routine drug use strategy were selected as the control group,and 68 patients who were hospitalized in the Department of Respiratory Medicine,Department of Gastroenterology,Department of Urology or Department of Cardiology of our hospital from July to December 2022 and implemented rational drug use strategy were selected as the observation group.The disease remission,occurrence of adverse reactions,quality of life,and medication compliance were compared between the two groups.Results The total remission rate of the observation group was 94.12%,which was significantly higher than 60.29%of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 5.88%,which was significantly lower than 35.29%in the control group,and the difference was statistically significant(P<0.05).The scores of physical function,physical role,bodily pain,general health,mental health,social function,mental role and health change in the observation group were(87.11±2.92),(89.35±3.11),(85.94±3.94),(90.12±2.82),(89.90±2.53),(91.73±3.55),(88.37±3.12)and(88.03±2.54)points,which were significantly higher than(74.26±3.27),(71.46±3.56),(71.09±4.64),(72.58±4.29),(72.31±3.79),(75.98±3.42),(73.30±3.68)and(72.14±4.13)points in the control group.The difference was statistically significant(P<0.05).The total compliance rate of the observation group was 94.12%,which was higher than 66.18%of the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with routine drug use strategy,rational drug use strategy in western medicine treatment has significant advantages in improving the remission rate

关 键 词：西药 合理用药 生活质量 不良反应 病情缓解率 用药依从性 

分 类 号：R969.3[医药卫生—药理学]