小切口非超声乳化术治疗硬核白内障患者的效果  

Effects of small incision non-phacoemulsification in treatment of patients with hard nucleus cataract

作　　者：黄卫斌 HUANG Weibin(Department of Ophthalmology and Otorhinolaryngology of Jinxian County People’s Hospital,Nanchang 331700 Jiangxi,China)

机构地区：[1]进贤县人民医院眼耳鼻喉科,江西南昌331700

出　　处：《中国民康医学》2024年第11期46-49,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察小切口非超声乳化术治疗硬核白内障患者的效果。方法:选取2020年11月至2023年5月该院收治的70例硬核白内障患者进行前瞻性研究,按照随机数字表法将其分为研究组和对照组各35例。对照组采用传统超声乳化术治疗,研究组采用小切口非超声乳化术治疗。比较两组临床疗效,手术前后临床指标(裸眼视力、眼压)水平、角膜功能指标(角膜内皮细胞密度、中央角膜厚度、泪膜破裂时间)水平、炎性指标[基质金属蛋白酶-9(MMP-9)、肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)]水平,以及并发症发生率。结果:研究组治疗总有效率为94.29%(33/35),高于对照组的77.14%(27/35),差异有统计学意义(P<0.05);术后1个月,研究组裸眼视力水平高于对照组,眼压水平低于对照组,差异均有统计学意义(P<0.05);术后1个月,研究组角膜内皮细胞密度、中央角膜厚度均高于对照组,泪膜破裂时间长于对照组,差异有统计学意义(P<0.05);术后7 d,研究组IL-1β、MMP-9、TNF-α水平均低于对照组,差异有统计学意义(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:小切口非超声乳化术治疗硬核白内障患者可提高治疗总有效率,改善临床指标和角膜功能指标水平,降低炎性指标水平,效果优于传统超声乳化术治疗。Objective:To observe effects of small incision non-phacoemulsification in treatment of patients with hard nucleus cataract.Methods:A prospective study was conducted on 70 patients with hard nucleus cataract admitted to the hospital from November 2020 to May 2023.According to the random number table method,they were divided into study group and control group,35 cases in each group.The control group was treated with traditional phacoemulsification,while the study group was treated with small incision non-phacoemulsification.The clinical efficacy,the levels of clinical indicators(uncorrected visual acuity,intraocular pressure),corneal function indicators(corneal endothelial cell density,central corneal thickness,tear film rupture time)and inflammatory indicators[matrix metalloproteinase-9(MMP-9),tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β)]before and after the surgery,and the incidence of complications were compared between the two groups.Results:The total effective rate of the study group was 94.29%(33/35),which was higher than 77.14%(27/35)of the control group,and the difference was statistically significant(P<0.05).1 month after the surgery,the uncorrected visual acuity level of the study group was higher than that of the control group,the intraocular pressure level was lower than that of the control group,and the differences were statistically significant(P<0.05).1 month after the surgery,the corneal endothelial cell density,tear film rupture time and central corneal thickness in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).7 days after the surgery,the levels of IL-1β,MMP-9 and TNF-αin the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusions:Small incision non-phacoemulsification in the treatment of the hard nucleus cataract patients can improve t

关 键 词：硬核白内障 超声乳化术 小切口非超声乳化术 视力 角膜功能 并发症 

分 类 号：R779.6[医药卫生—眼科]