血脂康胶囊联合阿托伐他汀治疗颈动脉粥样硬化患者的效果  

Effects of Xuezhikang capsules combined with Atorvastatin in treatment of patients with carotid atherosclerosis

作　　者：李香娜 LI Xiangna(Outpatient Western Medicine Pharmacy of Puyang Hospital of Traditional Chinese Medicine,Puyang 457000 Henan,China)

机构地区：[1]濮阳市中医医院门诊西药房,河南濮阳457000

出　　处：《中国民康医学》2024年第11期92-94,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察血脂康胶囊联合阿托伐他汀治疗颈动脉粥样硬化患者的效果。方法:回顾性分析2021年9月至2023年3月该院收治的120例颈动脉粥样硬化患者的临床资料,按照治疗方法不同分为观察组与对照组各60例。对照组口服阿托伐他汀钙片治疗,观察组在对照组基础上联合血脂康胶囊治疗。比较两组临床疗效,治疗前后颈动脉内膜中层厚度(IMT)、斑块面积、血脂[总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)]水平,以及不良反应发生率。结果:观察组治疗总有效率为95.00%(57/60),高于对照组的83.33%(50/60),差异有统计学意义(P<0.05);治疗后,观察组颈动脉IMT、斑块面积均小于对照组,TC、TG、LDL-C水平均低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:血脂康胶囊联合阿托伐他汀治疗颈动脉粥样硬化患者可提高治疗总有效率,缩小颈动脉IMT和斑块面积,降低TC、TG、LDL-C水平,效果优于单用阿伐他汀治疗。Objective:To observe effects of Xuezhikang capsules combined with Atorvastatin in treatment of patients with carotid atherosclerosis.Methods:The clinical data of 120 patients with carotid atherosclerosis admitted to this hospital from September 2021 to March 2023 were retrospectively analyzed.According to different treatment methods,they were divided into observation group and control group,60 cases in each group.The control group was treated with Atorvastatin calcium tablets orally,while the observation group was treated with Xuezhikang capsules on the basis of that of the control group.The clinical efficacy,the carotid intima-media thickness(IMT),the plaque area,the blood lipid[total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C)]levels,and the incidence of adverse reactions were compared between the two groups before and after the treatment.Results:The total effective rate of the observation group was 95.00%(57/60),which was higher than 83.33%(50/60)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the IMT and the plaque area of carotid artery in the observation group were smaller than those in the control group,the levels of TC,TG and LDL-C were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Xuezhikang capsules combined with Atorvastatin in the treatment of the patients with carotid atherosclerosis can improve the total effective rate of treatment,reduce the carotid IMT and the plaque area,and reduce the TC,TG and LDL-C levels.Moreover,it is superior to single Atorvastatin treatment.

关 键 词：阿托伐他汀 血脂康胶囊 颈动脉粥样硬化 血脂 颈动脉内膜中层厚度 斑块面积 

分 类 号：R544.1[医药卫生—心血管疾病]