雅培I2000发光仪检验血清雌激素、性激素表达水平对多囊卵巢综合症的诊断价值研究  

The Value of Detecting the Expression Levels of Serum Estrogen and Sex Hormone with Abbott I2000 Luminescence Instrument in the Diagnosis of Polycystic Ovary Syndrome

作　　者：沈安妮 SHEN An-ni(Department of Clinical Laboratory,Xiamen Eye Center,Xiamen University,Fujian Xiamen 361004)

机构地区：[1]厦门大学附属厦门眼科中心检验科,福建厦门361004

出　　处：《中国医疗器械信息》2024年第10期49-51,共3页China Medical Device Information

摘　　要：目的:分析雅培I2000发光仪检验血清雌激素、性激素表达水平对多囊卵巢综合症(PCOS)的诊断价值。方法:将院内2022年1月~2023年6月收治的PCOS患者50例作为观察组,另将同一时期接收的健康志愿者50名作为对照组,均采取雅培I2000发光仪检验,分析雅培I2000发光仪检验下不同研究对象雌激素、性激素表达水平改变情况;另将观察组按照PCOS国际诊断标准分组(1型、2型、3型、4型),分析不同亚型分型患者雅培I2000发光仪检验下的雌激素、性激素表达水平。结果:观察组促黄体生成素(LH)、促卵泡刺激素(FSH)、泌乳素(PRL)、睾酮(T)、孕酮(P)水平高于对照组,雌二醇(E2)水平低于对照组,对比差异有统计学意义(P<0.05);1型、2型、3型、4型患者FSH、PRL、T、P、LH增高顺序为:4型>3型>2型>1型,E2降低顺序为:4型<3型<2型<1型,对比差异有统计学意义(P<0.05)。结论:在PCOS疾病诊断中,用雅培I2000发光仪检验相关激素水平改变能够帮助临床明确PCOS疾病,还能通过雅培I2000发光仪检验的激素水平改变明确PCOS分型。Objective:To analyze the diagnostic value of serum estrogen and sex hormone expression levels by Abbott I2000 luminescence instrument in polycystic ovary syndrome(PCOS).Methods:50 PCOS patients admitted to the hospital in recent years(from January 2022 to June 2023)were selected as the observation group,and 50 healthy volunteers received during the same period were selected as the control group.All of them were tested by Abbott I2000 luminescence instrument.The expression levels of estrogen and sex hormone in different subjects were analyzed by Abbott I2000 luminescence apparatus.In addition,the observation group was divided according to PCOS international diagnostic standards(type 1,type 2,type 3,type 4),and the expression levels of estrogen and sex hormone in patients with different subtypes were analyzed under the detection of Abbott I2000 luminescence instrument.Results:The levels of luteinizing hormone(LH),follicle-stimulating hormone(FSH),prolactin(PRL),testosterone(T)and progesterone(P)in observation group were higher than those in control group,and the levels of estradiol(E2)were lower than those in control group,the difference was statistically significant(P<0.05).In patients with type 1,type 2,type 3 and type 4,the increase of FSH,PRL,T,P and LH was in the order of type 4>type 3>type 2>type 1,and the decrease of E2 was in the order of type 4<type 3<type 2<type 1,with statistical significance(P<0.05).Conclusion:In the diagnosis of PCOS disease,using Abbott I2000 luminescence instrument to test the change of related hormone levels can help to identify PCOS disease clinically,and can also identify PCOS classification through the change of hormone levels tested by Abbott I2000 luminescence instrument.

关 键 词：雅培I2000发光仪 激素 多囊卵巢综合征 

分 类 号：R446.1[医药卫生—诊断学]