儿童百日咳流行病学特征及临床特点的研究进展  

Research progress on epidemiological and clinical characteristics of pertussis in children

作　　者：张慧敏[1] 王天有[1] Zhang Huimin;Wang Tianyou(Hematology Center,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,Beijing 100045,China)

机构地区：[1]国家儿童医学中心,首都医科大学附属北京儿童医院血液病中心,100045

出　　处：《中国小儿急救医学》2024年第4期288-294,共7页Chinese Pediatric Emergency Medicine

摘　　要：疫苗高覆盖下,全世界范围仍出现了“百日咳再现”,不仅是婴幼儿,青少年及成人发病率亦显著增加。继续做好百日咳的防控,已成为全球的一个重大公共卫生问题。我国近几年百日咳也呈现上升趋势,但实际发病人数可能被严重低估,低估的原因涉及历史、现实及社会人文等因素。本文总结了国内外百日咳流行现状,通过对儿童百日咳临床特点的再认识,为百日咳诊断及预防提供参考思路。The resurgence of pertussis has been observed worldwide,despite high vaccination coverage.Not only there is a high incidence among infants and young children,but there has also been a significant increase in the number of affected adolescents and adults.This poses a major global public health issue in terms of preventing and controlling whooping cough.In recent years,pertussis has shown an upward trend in China as well.However,it is likely that the actual number of patients is seriously underestimated due to various historical,realistic,social and cultural factors.This review aimed to summarize the epidemic situation of pertussis both domestically and internationally,and provided insights into diagnosing and preventing pertussis by re-recognizing the clinical characteristics of pertussis in children.

关 键 词：百日咳 儿童 发病率 临床特点 实验室检查 

分 类 号：R725.1[医药卫生—儿科] R181.3[医药卫生—临床医学]