超声测定Tei指数和LVEDV、LVESV、SV评估足月小样儿心功能变化的研究  

Evaluation of cardiac function change in full-term sm all-for-date infant on Tei index,LVEDV,LVESV and SV measured by ultrasound

作　　者：靳雅玲 王亚东 李洁 何颖 范雪爱 JIN Ya-ling;WANG Ya-dong;Li Jie;HE Ying;FAN Xue-ai(Department of Child Healthcare,Xingtai Central Hospital,Xingtai 054000,Hebei,China;Department of Neonatology,Xingtai Central Hospital,Xingtai 054000,Hebei,China)

机构地区：[1]邢台市中心医院儿童保健科,河北邢台054099 [2]邢台市中心医院新生儿科,河北邢台054099

出　　处：《生物医学工程与临床》2024年第3期331-337,共7页Biomedical Engineering and Clinical Medicine

基　　金：邢台市科技局重点研发计划项目(2022zz082)。

摘　　要：目的探究超声测定心肌做功指数(Tei指数)和左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、每搏量(SV)对足月小样儿心功能变化评估价值。方法选择2020年11月至2022年11月在邢台市中心医院出生的100例足月小样儿(研究组),其中男性47例,女性53例;胎龄37~41+6周,平均胎龄39.62周;体质量2.07~2.43 kg,平均体质量2.12 kg。依据足月小样儿胎龄将新生儿分为早期足月小样儿(37~38+6周)组,晚期足月小样儿(39~41^(+6)周)组,每组50例。另选择医院同期出生的50例健康足月新生儿(对照组),其中男性25例,女性25例;胎龄38~40+6周,平均胎龄39.33周;体质量2.53~4.00 kg,平均体质量3.07 kg。采用超声测定3组Tei指数和LVEDV、LVESV、SV、左心室射血分数(LVEF)、心输出量(CO),左右心大血管内径、室壁厚度、心内径指标,二、三尖瓣心舒张功能指标,进而评估足月小样儿心功能变化情况。结果对照组、早期足月小样儿组、晚期足月小样儿组左右心室等容收缩期时间(ICT)+等容舒张期时间(IRT)、射血期时间(ET)依次降低,Tei指数依次升高,差异有统计学意义(P<0.05)。对照组、早期足月小样儿组、晚期足月小样儿组SV[(3.50±0.94)mL vs(2.96±0.63)mL vs(2.55±0.48)mL]、LVEDV[(5.07±1.19)m L vs(4.71±1.05)mL vs(4.49±0.93)mL]、LVEF[(71.53±4.52)%vs(66.19±3.21)%vs(63.44±2.98)%]、CO指数[(0.75±0.09)L/min vs(0.51±0.13)L/min vs(0.44±0.17)L/min]依次降低,LVESV指数依次升高[(1.46±0.37)mL vs(1.59±0.41)m L vs(1.66±0.43)mL],差异有统计学意义(P<0.05)。对照组、早期足月小样儿组、晚期足月小样儿组主动脉根部内径(AOD)[(6.9±1.0)mm vs(6.0±0.8)mm vs(5.5±0.5)mm]、左心室后壁舒张末期厚度(LVPWD)、左心房收缩期末期内径(LAD)、左心室收缩末期内径(LVDS)、左心室舒张末期内径(LVDD)指数依次降低,差异有统计学意义(F=39.947、37.000、27.820、34.742、27.990,P<0.05)。对照组、早期足月小样儿组�Objective To explore the evaluation value of Tei index,left ventricular end diastolic volume(LVEDV),left ventricular end systolic volume(LVESV),stroke volume(SV)and myocardial performance index(MPI)measured by ultrasound on cardiac function change in full-term small-for-date infant.Methods From November 2020 to November 2022,a total of 100full-term infants were enrolled as study group,which included 47 males and 53 females;gestational age was 37-41+6weeks with mean gestational age of 39.62 weeks;body mass was 2.07-2.43 kg with mean body mass of 2.12 kg.According to gesta tional age,the infants were divided into early full-term small-for-date infant group(37-38^(+6)weeks)and late full-term smallfor-date infant group(39-41+6weeks),with 50 cases in each group.Fifty healthy full-term newborns from the same period were enrolled as control group,which included 25 males and 25 females;gestational aged 38-40+6weeks with mean gestational age of 39.33 weeks;body mass was 2.53-4.00 kg with mean body mass of 3.07 kg.Tei index,LVEDV,LVESV,SV,left ventricular ejection fraction(LVEF),cardiac output(CO),left and right cardiac vascular diameter,wall thickness,cardiac diameter index,mitral and tricuspid diastolic function index were measured by ultrasound,and cardiac function changes in fullterm small-for-date infant were evaluated.Results The isovolumic contraction time(ICT)+isovolumic relaxation time(IRT)and ejection time(ET)of the left and right ventricles in control group,early full-term small-for-date infant group and late full-term small-for-date infant group were sequentially decreased,while Tei indexes of 3 groups sequentially increased,and the differences were statistically significant(P<0.05).The control group,early full-term small-for-date infant group and late full-term small-for-date infant group were observed sequentially decreased in SV[(3.50±0.94)mL vs(2.96±0.63)mL vs(2.55±0.48)mL],LVEDV[(5.07±1.19)mL vs(4.71±1.05)mL vs(4.49±0.93)mL],LVEF[(71.53±4.52)%vs(66.19±3.21)%vs(63.44±2.98)%],CO index[(0.75±0.09)L/

关 键 词：超声 Tei指数 左心室舒张末期容积(LVEDV) 左心室收缩末期容积(LVESV) 心搏量(SV) 足月小样儿 

分 类 号：R445.1[医药卫生—影像医学与核医学] R722[医药卫生—诊断学]