中医药调节干燥综合征唾液腺免疫微环境研究进展  

Research Progress on Regulation of Salivary Gland Immune Microenvironment by Traditional Chinese Medicine in Sjogrens Syndrome

作　　者：马敏 张杰[2] MA Min;ZHANG Jie(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;The First Affiliated Hospital of China Medical University,Shenyang 110032,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]中国医科大学附属第一医院,辽宁沈阳110032

出　　处：《实用中医内科杂志》2024年第6期31-33,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：国家自然科学基金项目(81973661)。

摘　　要：干燥综合征(SS)是一种慢性自身免疫性疾病,临床表现为口干、眼干。严重时会影响患者的生活质量。目前,SS尚无治愈方法,治疗选择极为有限。中医药治疗干燥综合征具有较好疗效,临床和实验研究常用益气滋阴润燥类方药,其作用机制包括对缺氧的改善作用,对慢性炎症的抑制作用,对衰老的调节作用等。缺氧、慢性炎症和衰老是唾液腺微环境的三大特征。该文从免疫微环境的角度对近年来有关中医药治疗SS患者唾液腺的研究进行综述。Sjogren's syndrome(SS)is a chronic autoimmune disease with clinical manifestations of dry mouth and dry eyes.In severe cases,it will affect the quality of life of patients.At present,there is no cure for SS,and the choice of treatment is very limited.Traditional Chinese medicine has a good effect in the treatment of SS.Prescription for replenishing Qi,nourishing Yin and moistening dryness is commonly used in clinical and experimental research.Its mechanism includes the improvement of hy-poxia,inhibition of chronic inflammation,regulation of aging and so on.Hypoxia,chronic inflammation and aging are the three major characteristics of salivary gland microenvironment.This article reviewed the recent studies on the treatment of salivary glands in patients with SS by traditional Chinese medicine from the point of view of immune microenvironment.

关 键 词：中医药 干燥综合征 免疫微环境 研究进展 

分 类 号：R259[医药卫生—中西医结合]