超声心动图评价室间隔-升主动脉夹角与S状室间隔患者升主动脉弹性的相关性  

The correlation between Aortoseptal angle and ascending aorta elasticity in patients with Sigmoid shaped interventricular septum by echocardiography

作　　者：杨小燕 夏纪筑 彭雪莲 张玉佩 李文兰 YANG Xiaoyan;XIA Jizhu;PENG Xuelian;ZHANG Yupei;LI Wenlan(Department of Ultrasound Medicine,The Affiliated Hospital of Southwest Medical University,Luzhou 646000,Sichuan,China)

机构地区：[1]西南医科大学附属医院超声医学科,四川泸州646000

出　　处：《西部医学》2024年第6期926-930,936,共6页Medical Journal of West China

基　　金：国家自然科学青年基金项目(2019ZQN085)。

摘　　要：目的探讨应用超声心动图评价室间隔-升主动脉夹角(Ao SA)与S状室间隔(SSIVS)患者升主动脉弹性的相关性。方法选择2021年8月-2022年4月本院确诊为SSIVS的患者82例为研究对象,按Ao SA的测值分为A组(≥120°,42例)和B组(<120°,40例);另选取年龄、性别相匹配的40例健康志愿者为对照组。二维超声测量常规超声心动图参数;M型超声测量收缩期升主动脉内径(ASD)、舒张期升主动脉内径(ADD);PW-TDI模式获得升主动脉前壁收缩期运动速度(S波)、舒张早期运动速度(E波)及舒张晚期运动速度(A波),比较各组人群的上述参数的差异,并评价Ao SA与SSIVS患者升主动脉弹性之间的相关性。结果与对照组相比,A组与B组患者的高血压比例明显增高,bIVS、mIVS、Vlvot、ASD、ADD增加,S波、E波降低,差异有统计学意义(均P<0.05);与A组相比,B组bIVS、ASD增加,S波减低,差异有统计学意义(均P<0.05),其余参数比较差异无统计学意义(均P>0.05)。Pearson相关分析显示,SSIVS患者的Ao SA与ASD、ADD呈负相关(r=-0.372、-0.325,P<0.05),与S波、E波呈正相关(r=410、0.329;P<0.05)。结论Ao SA与SSIVS患者升主动脉弹性相关,Ao SA越小升主动脉弹性功能越易受损,早期对Ao SA相对较小的SSIVS升主动脉弹性进行针对性评估,及时干预,有助于延缓并发症的发生。Objective To investigate the correlation between Aortoseptal angle(Ao SA)and ascending aorta elasticity in patients with Sigmoid shaped interventricular septum(SSIVS)by echocardiography.Methods A total of 82 patients with SSIVS were selected as the research objects.These patients were divided into A group(n=42)and B group(n=40)according to the Ao SA.Another 40 healthy volunteers matched in age and sex were selected as the control group.Conventional echocardiographic data were measured by two-dimensional ultrasound.The Systolic diameter of AAO(ASD)and diastolic diameter of AAO(ADD)were measured by M-mode echocardiography.The peak velocity during systole(SAo),early contraction peak velocity during diastole(EAo),and late contraction peak velocities during diastole were measured by tissue Doppler imaging.Then the differences of the above data were compared among the groups,and the correlation between Ao SA and the elasticity of ascending aorta in patients with SSIVS was evaluated.Results Compared with the control group,the proportion of hypertension in SSIVS was significantly increased,and bIVS,mIVS,Vlvot,ASD,ADD were increased,SAo and EAo were decreased.Compared with group A,bIVS and ASD were increased,and SAo was decreased in group B(P<0.05).Pearon correlation analysis showed that Ao SA was negatively correlated with ASD,ADD(r=-0.372,-0.325;P<0.05),and positively correlated with SAo,EAo(r=0.410,0.329;P<0.05).Conclusion Ao SA is related to the elasticity of ascending aorta in patients with SSIVS,When the Ao SA decreases,the ascending aorta elasticity is vulnerable to damage.Early targeted assessment of the ascending aorta elasticity in patients with relatively small Ao SA and timely intervention are helpful to delay the occurrence of complications.

关 键 词：室间隔-升主动脉夹角 升主动脉弹性 S状室间隔 超声心动图 心脏疾病 

分 类 号：R543.12[医药卫生—心血管疾病]