加味芍药甘草汤联合耳穴埋针对肠燥津亏型老年功能性便秘的疗效观察  

Observation of the clinical efficacy of modified Shaoyao gancao tang combined with ear acupoint embedding for elderly functional constipation patients with intestinal dryness and fluid deficiency

作　　者：赵书奇 孙粼 刘帅[1] 朱婷玉 ZHAO Shuqi;SUN Lin;LIU Shuai;ZHU Tingyu(Traditional Chinese Medicine Department of Huacao Community Health Service Center of Minhang District,Shanghai 201107,China;Shanghai Traditional Chinese Medicine Geriatrics Research Institute,Shanghai 200031,China)

机构地区：[1]上海市闵行区华漕社区卫生服务中心中医科,上海201107 [2]上海市中医老年医学研究所,上海200031

出　　处：《上海医药》2024年第4期34-37,53,共5页Shanghai Medical & Pharmaceutical Journal

基　　金：上海市闵行区自然科学研究课题资助(2021MHZ058)。

摘　　要：目的:观察自拟加味芍药甘草汤联合耳穴埋针对肠燥津亏型老年功能性便秘患者的临床疗效并评估生存质量。方法:选取2020年4月至2022年10月就诊于上海市闵行区华漕社区卫生服务中心的111例肠燥津亏型老年功能性便秘患者,按随机数字表法分成西药组、中药组、针药组各37例。西药组口服莫沙必利每次5 mg,每天3次,连续14 d。中药组口服加味芍药甘草汤每天200 mL,分2次服用,疗程14 d。针药组予加味芍药甘草汤联合耳穴埋针治疗,疗程14 d。三组分别在治疗前及治疗2周后对便秘症状改善程度、有效率、安全性进行对比,采用生存质量自评量表(PAC-QOL)进行评估。结果:针药组有效率91.89%(34/37),中药组有效率89.19%(33/37),两组均高于西药组的78.38%(29/37,P<0.05)。干预后,针药组和中药组的腹胀程度评分优于西药组(P<0.05)。西药组不良反应发生率为5.41%,中药组为2.7%,针药组无不良反应(P>0.05)。干预后,针药组PAC-QOL总评分优于中药组和西药组(P<0.05),在担心与焦虑、满意度两项评分上存在显著性差异(P<0.01)。结论:加味芍药甘草汤联合耳穴埋针对肠燥津亏型老年功能性便秘患者疗效确切,能显著改善患者的腹胀程度,减轻患者焦虑心态,提高疗效满意度。Objective:To observe the clinical efficacy of self-made modified Shaoyao gancao tang combined with ear acupoint embedding for elderly functional constipation patients with intestinal dryness and fluid deficiency and evaluate the quality of life.Methods:One hundred and eleven elderly functional constipation patients with intestinal dryness and fluid deficiency who visited the Huacao Community Health Service Center in Minhang District,Shanghai from April 2020 to October 2022 were selected and divided into a Western medicine group,a Chinese medicine group,and an acupuncture and medicine group with 37 cases each with random number table method.The Western medicine group was treated with mosapride 5 mg each time,3 times a day,for 14 consecutive days,the Chinese medicine group was treated with modified Shaoyao gancao tang 200 mL daily in 2 doses for a 14-day course,and the acupuncture and medicine group were treated with modified Shaoyao gancao tang combined with ear acupoint embedding for 14 days course.Three groups were compared in terms of improvement,effectiveness,and safety before and after 2 weeks of treatment,and evaluated with patient assessment of constipation quality of life scale(PAC-QOL).Results:The effective rate of the acupuncture and medicine group was 91.89%(34/37),the effective rate of the Chinese medicine group was 89.19%(33/37),both groups were higher than 78.38%(29/37)of the Western medicine group(P<0.05);after intervention,the abdominal distension scores in the acupuncture and medicine and Chinese medicine groups were better than that in the Western medicine group(P<0.05).The incidence of adverse reactions in the Western medicine group was 5.41%,the Chinese medicine group was 2.7%,and there was no adverse reaction in the acupuncture and medicine group(P>0.05);after intervention,the total score of PAC-QOL in the acupuncture and medicine group was better than that in the Chinese medicine group and the Western medicine group(P<0.05),and there was a significant difference in the scores of worry and anx

关 键 词：功能性便秘 芍药甘草汤 耳穴 肠燥津亏 老年人 

分 类 号：R256.352.2[医药卫生—中医内科学]