电化学免疫传感器中纳米材料信号放大策略的研究进展  

Research Progress on Signal Amplification Strategies of Nanomaterials in Electrochemical Immunosensors

作　　者：朱蕾静 安雅睿 ZHU Leijing;AN Yarui(Institute of Bismuth and Rhenium,School of Materials and Chemistry,University of Shanghai for Science and Technology,Shanghai 200093,China)

机构地区：[1]上海理工大学材料与化学学院,铋铼科学研究中心,上海200093

出　　处：《理化检验（化学分册）》2024年第5期536-548,共13页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：国家自然科学基金青年项目(No.21505092)。

摘　　要：简单介绍了电化学免疫传感器的构成及原理,详细从导电性增强、信号分子富集、抗体增加、催化信号放大等4个方面进行纳米材料信号放大策略的综述。其中重点分析了各类纳米材料,包括石墨烯类纳米材料、金属纳米材料、多孔纳米材料、磁性纳米材料和金属化合物纳米材料的功能特性及信号放大原理。其次,总结了基于纳米材料信号放大策略的电化学免疫传感器对不同领域分析物的检测,提出了基于纳米材料的电化学免疫传感器目前面临的问题,并对其今后发展存在的机遇进行了展望(引用文献79篇)。The structure and principle of electrochemical immunosensors were briefly introduced,and the signal amplification strategies of nanomaterials were reviewed in detail from four aspects including electrical conductivity enhancement,signal molecule enrichment,antibody increasing and catalytic signal amplification.The functional properties and signal amplification principle of various nanomaterials,including graphene nanomaterials,metal nanomaterials,porous nanomaterials,magnetic nanomaterials and metal compound nanomaterials,were analyzed emphatically.Then the detections of analytes in different fields by electrochemical immunosensors based on the signal amplification strategy of nanomaterials were summarized.The current problems of electrochemical immunosensors based on nanomaterials were presented and the opportunity for their future development was prospected(79 ref.cited).

关 键 词：纳米材料 信号放大策略 电化学传感器 免疫分析 传感界面 

分 类 号：O65[理学—分析化学]