重构本草——秦皮  

Reconstruction of Chinese materia medica-ash bark

作　　者：赵金悦 李佳芮 谢娜 于泳江 段丽云 ZHAO Jinyue;LI Jiarui;XIE Na;YU Yongjiang;DUAN Liyun(Changchun University of Chinese Medicine,Changchun 130117,China;The Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China;The Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China;Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

机构地区：[1]长春中医药大学,长春130117 [2]山东中医药大学附属医院,济南250014 [3]长春中医药大学附属医院,长春130021 [4]山东中医药大学,济南250355

出　　处：《长春中医药大学学报》2024年第6期609-611,共3页Journal of Changchun University of Chinese Medicine

基　　金：中国科学院学部咨询评议项目(2021-ZW10-A-017);国家自然科学基金面上项目(81973837)。

摘　　要：通过古籍文献调研、中医药现代研究成果的梳理,结合中医临床及中药学等学科领域内知名专家学者的认识及应用经验,归纳出秦皮:功效主要为清热燥湿,收涩止痢,止带,明目。症靶为腹泻、痛风、目赤肿痛等。标靶为高尿酸。现代药理研究发现,秦皮及其有效成分具有抗菌抗炎、抗氧化、抗肿瘤、降低血尿酸等作用。本品无毒,但脾胃虚寒者慎服。临床常用剂量为6~30 g,内服时当根据不同疾病,或同一疾病的不同阶段进行辨证使用,并积极探索秦皮用量与症靶、标靶的量效关系构建。Through the investigation of ancient books and the sorting of the modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of well-known experts and scholars in desciplinary fields such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that ash bark mainly has the effects of clearing heat and removing dampness,astriction and relieving dysentery,arresting leucorrhea,and improving eyesight.The symptom targets are diarrhea,gout,red eye,and swelling and pain of eye.The biochemical indicator target is hyperuricemia.Modern pharmacological studies have found that ash bark and its active ingredients have the effects of antisepsis,anti-inflammatory,anti-oxidation,anti-tumor,and decreasing serum uric acid levels.This medicine is non-toxic,but the patients with deficient cold of spleen and stomach should take it with caution.The clinical dosage is 6-30g.When taken orally,it should be used dialectically according to different diseases or different stages of the same disease,and the construction of dose-effect relationship between the dosage of ash bark and the symptom target and biochemical indicator target should be explored actively.

关 键 词：秦皮 症靶 标靶 重构本草 临床回归 

分 类 号：R282[医药卫生—中药学]