蜱传脑炎概况及其防治研究进展  

Overview of tick-borne encephalitis and research progress in prevention and control

作　　者：张芳 王小恒[1] ZHANG Fang;WANG Xiao-heng(Department of Medicine,Northwest Minzu University,Lanzhou 730030,China)

机构地区：[1]西北民族大学医学部,兰州730030

出　　处：《中国人兽共患病学报》2024年第4期346-351,共6页Chinese Journal of Zoonoses

基　　金：中央高校基本科研业务费专项资金项目资助(No.31920230191);西北民族大学引进人才项目(No.xbmuyjr202234)联合资助。

摘　　要：蜱传脑炎病毒(Tick-borne encephalitis virus,TBEV)是引起中枢神经系统疾病——蜱传脑炎(Tick-borne encephalitis,TBE)的病原体,可在人与动物中引起致死性脑炎并伴有长期的后遗症,严重影响人类健康与公共卫生安全。近年来随着气候变化以及人类对自然资源的开发,蜱传脑炎发病率不断升高,但目前尚无有效的治疗药物,靶向抗病毒药物的研发是治疗病毒感染的主要方向之一。蜱传脑炎的预防主要集中在减少传播媒介蜱的叮咬上。本文对蜱传脑炎病毒的病原学特征、临床特征、检测诊断方法以及防治措施进行综述,以期为相关研究提供参考。Tick-borne encephalitis virus(TBEV)is the causative agent of the neurological disease tick-borne encephalitis(TBE),which can cause lethal encephalitis in human and animals with long-term sequelae,thus posing a great threat to life and public health.With the development of natural resources and climate change,the incidence of tick-borne encephalitis has continued to increase.However,there are no effective drugs for treatment of TBEV.Targeted anti-TBEV inhibitors have potential for treatment of TBEV infection.Prevention of TBEV infection has mainly focused on avoiding tick bites.In this paper,the pathogenic characteristics,clinical features,detection,diagnosis,prevention,and treatment of TBEV infection are reviewed,as references for related research.

关 键 词：蜱传脑炎病毒 病原学 防治 蜱 

分 类 号：R373.3[医药卫生—病原生物学]