中药药浴联合紫草膏涂抹对新生儿毒性红斑的疗效研究  

Study on the curative effect of traditional Chinese medicine bath combined with Zicao ointment on erythema toxicum neonatorum

作　　者：毛清芬 朱翡翡[1] 李艳平 MAO Qing-fen;ZHU Fei-fei;LI Yan-ping(Department of Obstetrics and Gynecology,Hangzhou Traditional Chinese Medicine Hospital,Hangzhou,Zhejiang 310007,Chi)

机构地区：[1]杭州市中医院妇一科,浙江杭州310007

出　　处：《中国妇幼保健》2024年第10期1779-1782,共4页Maternal and Child Health Care of China

基　　金：浙江省中医药科技计划项目(2023ZL543)。

摘　　要：目的 研究中药药浴联合紫草膏涂抹对新生儿毒性红斑的疗效。方法 选取2023年1-6月在杭州市中医院诊断为新生儿毒性红斑的患儿176例,随机分为空白组、紫草膏组、药浴组、药浴联合紫草膏组,每组44例。空白组采用常规水浴疗法,紫草膏组采用常规水浴后紫草膏涂抹红斑,药浴组采用常规水浴中加入中药包,药浴联合紫草膏组采用药浴后紫草膏涂抹红斑。干预2 d后评价4组患儿的临床疗效、红斑消退时间、中医症状积分及继发感染情况。结果 空白组、紫草膏组、药浴组及药浴联合紫草膏组治疗总有效率分别为77.27%、88.64%、86.36%、95.45%,药浴联合紫草膏组治疗总有效率最高,显著高于空白组,差异有统计学意义(P<0.05)。空白组、紫草膏组、药浴组、药浴联合紫草膏组患儿红斑消退时间分别为(38.21±5.43)h、(31.53±4.86)h、(33.49±3.04)h、(29.78±4.10)h,差异有统计学意义(P<0.05),药浴联合紫草膏组毒性红斑消退最快。治疗前4组中医症状积分比较,差异无统计学意义(P>0.05),治疗后4组中医症状积分均显著降低,空白组、紫草膏组、药浴组及药浴联合紫草膏组分别为(1.45±0.28)分、(1.29±0.31)分、(1.26±0.37)分、(1.03±0.22)分,以药浴联合紫草膏组降低最为显著(P<0.05)。空白组、紫草膏组、药浴组及药浴联合紫草膏组继发感染率分别为11.36%、6.82%、9.09%、4.55%,差异无统计学意义(P>0.05)。结论 中药药浴联合紫草膏涂抹对新生儿毒性红斑的疗效显著,不仅能够提高治疗总有效率,还可加快毒性红斑消退速度,是安全有效的治疗方案,值得应用。Objective To study the curative effect of traditional Chinese medicine bath combined with Zicao ointment on erythema toxi-cum neonatorum.Methods 176 children diagnosed with erythema toxicum neonatorum in Hangzhou Hospital of Traditional Chinese Medi-cine from January 2023 to June 2023 were randomly divided into blank group,lithospermum ointment group,medicated bath group and medicated bath combined with lithospermum ointment group,with 44 cases in each group.The blank group was treated with conventional wa-ter bath therapy,the lithospermum ointment group was smeared with erythema after conventional water bath,the medicated bath group was added with traditional Chinese medicine package in conventional water bath,the medicated bath combined with lithospermum ointment group was smeared with erythema after medicated bath.Afier 2 days of intervention,the clinical efficacy,erythema regression time,TCM symp-tom score and secondary infection of the four groups were evaluated.Results The total effective rates of the blank group,the Zicao ointment group,the medicated bath group and the medicated bath combined with Zicao ointment group were 77.27%,88.64%,86.36%and 95.45%,respectively.The total effective rate of the medicated bath combined with Zicao ointment group was the highest,which was signifi-cantly higher than that of the blank group,and the difference was statistically significant(P<0.05).The regression time of blank group lithospermum ointment group,medicated bath group,and medicated bath combined with lithospermum ointment group were(38.21±5.43)h,(31.53±4.86)h,(33.49±3.04)h and(29.78±4.10)h,there was a statistically significant difference(P<0.05).After treatment,the TCM symptom scores of the four groups were significantly reduced,the scores of blank group,lithospermum ointment group,medicated bath group,and medicated bath combined with lithospermum ointment group were(1.45±0.28)points,(1.29±0.31)points,(1.26±0.37)points and(1.03±0.22)points,the medicated bath combined with lithospermum ointment group was th

关 键 词：新生儿毒性红斑 中药 药浴 紫草膏 

分 类 号：R758.61[医药卫生—皮肤病学与性病学]