心脏手术相关急性肾损伤研究进展  

Update advances in cardiac surgery-associated acute kidney injury

作　　者：侯骉 李扬[1] 董然[1] Hou Biao;Li Yang;Dong Ran(Department of Cardiac Surgery,Beijing Anzhen Hospital Affiliated to Capital Medical University,Beijing 100029,China;Graduate School of Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京安贞医院心外科,北京100029 [2]首都医科大学研究生院,北京100069

出　　处：《中华胸心血管外科杂志》2024年第4期241-247,共7页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：北京市属医院科研培育计划(PX2023024)。

摘　　要：心脏手术相关急性肾损伤(cardiac surgery-associated acute kidney injury,CSA-AKI)是指心脏手术后出现的肾脏损伤,是心脏手术病死率增加和发展为慢性肾病的主要危险因素。CSA-AKI的病理生理过程复杂,危险因素繁多,早期诊断困难,防治策略研究进展缓慢。鉴于CSA-AKI的高发病率、高病死率及其造成的巨大社会经济负担,本文系统性综述CSA-AKI的病理生理学发病机制、危险因素、诊断标准以及防治策略的最新研究进展。Cardiac surgery-associated acute kidney injury(CSA-AKI)refers to kidney damage that occurs after cardiac surgery.It is a significant risk factor for increased mortality and the development of chronic kidney disease.The pathophysiology of CSA-AKI is complex,with numerous risk factors.Early diagnosis is challenging,and research on prevention and treatment strategies is slow.To give the high morbidity and mortality rates associated with CSA-AKI,and its significant socio-economic burden,this review systematically describes the latest advances in the pathophysiological pathogenesis,risk factors,diagnostic criteria,and prevention and treatment strategies of CSA-AKI.

关 键 词：社会经济负担 系统性综述 病理生理学 慢性肾病 肾脏损伤 防治策略 危险因素 

分 类 号：R654.2[医药卫生—外科学] R692[医药卫生—临床医学]