动态对比增强磁共振成像联合扩散加权成像对前列腺中央腺体癌的诊断价值  

Significance of DCE-MRI combined with DWI in the diagnosis of central gland prostate cancer

作　　者：孟静 杨雪丽 Meng Jing;Yang Xueli(Department of Imaging,Luohe Central Hospital,Luohe 462000,China)

机构地区：[1]漯河市中心医院影像科,漯河462000

出　　处：《中国实用医刊》2024年第5期79-82,共4页Chinese Journal of Practical Medicine

摘　　要：目的分析动态对比增强磁共振成像(DCE-MRI)联合扩散加权成像(DWI)对前列腺中央腺体癌的诊断价值。方法观察性研究。抽取2021年4月至2023年4月漯河市中心医院收治的68例疑似前列腺中央腺体癌患者作为研究对象。均行DCE-MRI、DWI诊断,以病理结果为"金标准",比较DCE-MRI、DWI诊断前列腺中央腺体癌的诊断结果、诊断效能,并比较前列腺中央腺体癌和中央腺体增生患者容量转移常数(Ktrans)、速率常数(Kep)、表观扩散系数(ADC值)。结果68例疑似前列腺中央腺体癌者,经病理结果诊断出前列腺中央腺体癌35例,中央腺体增生33例;采用DCE-MRI诊断出前列腺中央腺体癌34例,中央腺体增生34例;采用DWI诊断出前列腺中央腺体癌34例,中央腺体增生34例;DCE-MRI联合DWI诊断出前列腺中央腺体癌37例,中央腺体增生31例。DCE-MRI联合DWI诊断的灵敏度(97.14%,34/35)、准确度(94.12%,64/68)高于DCE-MRI诊断(77.14%,27/35;77.94%,53/68)和DWI诊断(80.00%,28/35;80.88%,55/68),P<0.05。前列腺中央腺体癌患者Ktrans、Kep高于中央腺体增生患者,ADC值低于中央腺体增生患者(P<0.05)。结论DCE-MRI联合DWI诊断前列腺中央腺体癌,能为临床诊断提供更多影像学数据支持,可显著提高诊断效能。Objective To analyze the significance of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with diffusion-weighted imaging(DWI)in the diagnosis of central gland prostate cancer.Methods This study was an observational study.A total of 68 patients with suspected central gland prostate cancer treated in Luohe Central Hospital from April 2021 to April 2023 were selected as the research objects.All patients underwent DCE-MRI and DWI.The diagnostic results and diagnostic efficacy of DCE-MRI and DWI in the diagnosis of central gland prostate cancer were compared.The transfer constant(Ktrans),rate constant(Kep)and apparent diffusion coefficient(ADC)values of patients with central gland prostate cancer and central gland hyperplasia were compared.Results Among 68 cases of suspected central gland prostate cancer,pathological results identifed 35 cases of central gland prostate cancer and 33 cases of central gland hyperplasia;34 cases of central gland prostate cancer and 34 cases of central gland hyperplasia were detected out by DCE-MRI;34 cases of central gland prostate cancer and 34 cases of central gland hyperplasia were detected out by DWI;37 cases of central gland prostate cancer and 31 cases of central gland hyperplasia were detected out by DCE-MRI combined with DWI.The diagnostic sensitivity and accuracy of DCE-MRI combined with DWI(97.14%,34/35;94.12%,64/68)were higher than those of DCE-MRI(77.14%,27/35;77.94%,53/68)and DWI(80.00%,28/35;80.88%,55/68),P<0.05.The Ktrans and Kep values of patients with central gland prostate cancer were higher,and the ADC value was lower compared with patients with central gland hyperplasia(P<0.05).Conclusions DCE-MRI combined with DWI in the diagnosis of central gland prostate cancer can provide more imaging data support for clinical diagnosis,and can significantly improve the diagnostic efficiency.

关 键 词：前列腺癌 动态对比增强磁共振成像 扩散加权成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]