COOK宫颈扩张球囊联合缩宫素与单用地诺前列酮栓在妊娠晚期引产中的应用效果对比  

Comparison of effect of Cook cervical ripening balloon combined with oxytocin versus dinoprostone suppositories alone in late-term pregnancy induced labor

作　　者：翁玲玲 王川红[1] 冯秀梅[1] Weng Lingling;Wang Chuanhong;Feng Xiumei(Ward I,Department of Obstetrics,Women and Infant Hospital of Zhengzhou,Zhengzhou 450000,China)

机构地区：[1]郑州市妇幼保健院产科一区,郑州450000

出　　处：《中国实用医刊》2024年第6期33-37,共5页Chinese Journal of Practical Medicine

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20220878)。

摘　　要：目的比较COOK宫颈扩张球囊联合缩宫素及单用地诺前列酮栓在妊娠晚期引产中的应用价值。方法队列研究。抽取2022年6月至2023年6月郑州市妇幼保健院收治的具有引产指征的孕晚期孕妇300例,按随机数字表法分为对照组与研究组,每组150例。对照组采用地诺前列酮栓(欣普贝生),研究组采用COOK宫颈扩张球囊联合缩宫素。比较两组Bishop宫颈成熟度评分、产程进展状况、引产成功率、分娩方式、产后出血量、新生儿状况、新生儿结局。结果治疗6、12、24 h后,研究组Bishop宫颈成熟度评分高于对照组(P<0.05)。研究组第一产程、第二产程、总产程及诱发临产时间短于对照组(P<0.05)。研究组引产成功率(88.67%,133/150)、正常分娩率(80.67%,121/150)高于对照组(64.00%,96/150;55.33%,83/150),且研究组阴道助产率(8.00%,12/150)、剖宫产率(11.33%,17/150)低于对照组(11.33%,17/150;33.33%,50/150),差异有统计学意义(P<0.05)。研究组产后2、24 h出血量少于对照组(P<0.05)。研究组肤色、呼吸、四肢肌张力、Apgar新生儿评分高于对照组(P<0.05)。研究组胎儿窘迫、急产、胎盘早剥、产后出血、新生儿窒息发生率低于对照组(P<0.05)。结论COOK宫颈扩张球囊联合缩宫素在妊娠晚期引产中能提高宫颈成熟度,缩短产程及临产时间,提升引产成功率,确保孕妇正常分娩和新生儿状况,降低助产及剖宫产发生率,减少产后出血量,且二者联合能减少新生儿不良结局发生率。Objective To compare the application value of Cook cervical ripening balloon combined with oxytocin and dinoprostone suppositories alone in late-term pregnancy induced labor.Methods A total of 300 pregnant women at late term with signs of induction of labor admitted to Women and Infant Hospital of Zhengzhou from June 2022 to June 2023 were selected for the cohort study.And they were divided into control group and study group according to random number table method,with 150 cases in each group.The control group was given dinoprostol supposit(hinprexine),and the study group was given Cook cervical ripening balloon combined with oxytocin treatment.The Bishop cervical maturity score,labor process progress condition,success rate of induced labor,delivery mode,amount of postpartum hemorrhage,newborn status and newborn outcome were compared between the two groups.Results Compared with the control group after 6,12,and 24 hours of treatment,the Bishop cervical maturity score in the study group was higher(P<0.05).Compared with the control group,the duration of the first stage of labor,duration of the second stage of labor,duration of the total stage of labor and time of induced labor in the study group were shorter(P<0.05).The success rate of induced labor and rate of normal delivery in the study group(88.67%,133/150;80.67%,121/150)were higher than those in the control group(64.00%,96/150;55.33%,83/150),moreover,the rate of assisted vaginal delivery and rate of caesarean section in the study group(8.00%,12/150;11.33%,17/150)were lower than those in the control group(11.33%,17/150;33.33%,50/150),P<0.05.Compared with the control group,the amount of 2-hour and 4-hour postpartum hemorrhage in the study group were less(P<0.05).Compared with the control group,the skin color score,respiration score,limb muscle tone score,and Apgar neonatal score in the study group were higher(P<0.05).The incidence of fetal distress,acute labor,placental abruption,postpartum hemorrhage and neonatal asphyxia in the study group were lower than those

关 键 词：引产 妊娠晚期 COOK宫颈扩张球囊 缩宫素 地诺前列酮栓 

分 类 号：R719.3[医药卫生—妇产科学]