人参消渴饮联合认知宣教治疗糖尿病前期脾虚痰湿证49例临床观察  

Clinical observation on 49 cases of spleen deficiency phlegm-dampness syndrome of prediabetes treated by Renshen Xiaoke Yin(人参消渴饮)combined with cognitive education

作　　者：周怀霞 许益国 ZHOU Huaixia;XU Yiguo(Department of Endocrinology,Qingyang Hospital of Chinese Medicine,Qingyang,Gansu,745000,China;Department of Clinical Laboratory,Qingyang Hospital of Chinese Medicine,Qingyang,Gansu,745000,China)

机构地区：[1]庆阳市中医医院内分泌科,甘肃庆阳745000 [2]庆阳市中医医院检验科,甘肃庆阳745000

出　　处：《甘肃中医药大学学报》2024年第2期70-74,共5页Journal of Gansu University of Chinese Medicine

基　　金：庆阳市科技计划项目(生物医疗与健康产业类)(QY2021A-S017)。

摘　　要：目的观察人参消渴饮联合认知宣教治疗糖尿病前期脾虚痰湿证的临床疗效。方法将98例糖尿病前期脾虚痰湿证患者采用随机数字表法分为对照组和治疗组,各49例。对照组予盐酸二甲双胍片口服治疗,治疗组予人参消渴饮联合认知宣教治疗,2组疗程均为12周。治疗后比较2组的临床疗效,以及治疗前后生活质量健康调查简表(SF-36)评分,中医证候积分,体质量指数(BMI),胰岛素抵抗指数(HOMA-IR),空腹血糖(FBG)、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)水平。结果对照组总有效率为63.27%(31/49),治疗组为85.71%(42/49),2组比较差异有统计学意义(P<0.05);治疗后2组中医证候积分、BMI、HOMA-IR及FBG、HbA1c、FINS水平均明显降低,SF-36评分均明显升高,与同组治疗前比较差异有统计学意义(P<0.05),且治疗组改善更明显,与对照组治疗后比较差异均有统计学意义(P<0.05)。结论人参消渴饮联合认知宣教治疗糖尿病前期脾虚痰湿证不仅能有效改善患者胰岛素抵抗和糖脂代谢,还能有效提升患者的身心健康,综合疗效显著,值得临床推广应用。Objective To observe the clinical efficacy of Renshen Xiaoke Yin(人参消渴饮)combined with cognitive education in the treatment of spleen deficiency phlegm-dampness syndrome of prediabetes.Methods Ninety-eight prediabetic patients presenting with spleen deficiency phlegm-dampness syndrome were randomly assigned to either a control group or a treatment group using random number table method,with 49 cases in each group.The control group received metformin hydrochloride tablets,while the treatment group was administered Renshen Xiaoke Yin combined with cognitive education.Both groups underwent a 12-week course of treatment.Following treatment,the clinical efficacy between the two groups was compared,along with SF-36 scores,TCM syndrome scores,body mass index(BMI),homeostasis model assessment of insulin resistance index(HOMA-IR),fasting blood glucose(FBG),HbA1c and fasting insulin(FINS)levels before and after treatment.Results The total effective rate was 63.27%(31/49)in the control group and 85.71%(42/49)in the treatment group,demonstrating statistically significant differences between the two groups(P<0.05).After treatment,TCM syndrome scores,BMI,HOMA-IR,FBG,HbA1c and FINS levels significantly decreased in both groups while SF-36 scores significantly increased,with statistical significance compared with the same group before treatment(P<0.05).These improvements were more pronounced in the treatment group which also showed statistically significant differences when compared to the control group post-treatment(P<0.05).Conclusion Renshen Xiaoke Yin combined with cognitive education for spleen deficiency phlegm-dampness syndrome of prediabetes not only effectively improves insulin resistance and glycolipid metabolism but also enhances physical and mental health outcomes for patients.Its comprehensive effects are significant,so it is worthy of clinical application.

关 键 词：糖尿病前期 脾虚痰湿证 人参消渴饮 认知宣教 糖脂代谢 胰岛素抵抗 临床疗效 

分 类 号：R259.871[医药卫生—中西医结合]