重庆市男性大学生久坐和体育运动与心理健康问题和睾酮水平的关联研究  

Associations of sedentary behaviour and physical activity with mental health problems and testosterone levels among male college students in Chongqing, China

作　　者：万梅 王立宏 凌曦 陈卿[2] 孙磊[2] 杨桓[2] 刘晋祎[2] 敖琳[2] 曹佳 邹鹏[2] WAN Mei;WANG Lihong;LING Xi;CHEN Qing;SUN Lei;YANG Huan;LIU Jinyi;AO Lin;CAO Jia;ZOU Peng(Department of Occupational Health,School of Public Health,Shanxi Medical University,Taiyuan 030001,China;Institute of Toxicology,College of Preventive Medicine,Army Medical University(Third Military Medical University),Chongqing 400038,China;West China School of Public Health,Sichuan University,Chengdu,610041,China)

机构地区：[1]山西医科大学公共卫生学院劳动卫生学教研室,太原030001 [2]陆军军医大学(第三军医大学)军事预防医学系军事毒理学教研室,重庆400038 [3]四川大学华西公共卫生学院,成都610041

出　　处：《中华疾病控制杂志》2024年第5期535-539,553,共6页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(82003429)。

摘　　要：目的 探讨重庆市男性大学生久坐和体育运动与心理健康问题和睾酮等激素水平的关联。方法 研究对象为582名来自重庆市男性大学生生殖健康队列(2015年)的大学生。问卷收集人口统计学、久坐、体育运动和心理健康数据,体育运动根据《体育运动等级量表》得分进行四分位数分类,分为Q1、Q2、Q3、Q4组。使用化学发光酶免疫法测定血清睾酮和皮质醇水平,使用logistic回归和线性回归模型分析久坐和体育运动与心理健康问题、睾酮和皮质醇水平的关联。结果 582名男性大学生抑郁、焦虑和压力症状的发生率分别为6.70%、12.71%和6.70%。与久坐<6 h组比较,久坐>10 h组抑郁症状的发生风险增加5.66倍(OR=6.66,95%CI:2.16~20.49,P=0.001),睾酮水平减少13.22%(95%CI:-19.56%~-6.37%,P<0.001);与体育运动Q1组比较,体育运动Q4组抑郁症状的发生率减少至66.00%(95%CI:0.13~0.87,P=0.025),睾酮水平增加8.02%(95%CI:1.37%~15.10%,P=0.017)。进一步分析发现,在高体育运动水平大学生中,久坐与抑郁、焦虑、压力症状及睾酮、皮质醇水平和睾酮/皮质醇比值的差异均无统计学意义(均P>0.05)。结论 久坐是大学生抑郁症状和睾酮水平降低的危险因素,体育运动是抑郁症状发生的保护因素,并与睾酮水平的升高有关,且体育运动可能缓解久坐的不良影响。Objective To investigate the associations of sedentary behaviour and physical activity(PA)with mental health problems and testosterone levels in male college students from Chongqing,China.Methods A total of 582 college students from the Male Reproductive Health in Chongqing College Students(MARHCS)cohort study in 2015 were included.Participants completed a questionnaire assessing demographics,sedentary behaviour,PA and mental health information.Physical activity was classified into quartiles based on scores on the physical activity rating scale-3,resulting in the following groups:Q1,Q2,Q3,and Q4.Serum testosterone and cortisol levels were measured by chemiluminescent enzyme immunoassay.Logistic and linear regressions model were used to analyze associations of sedentary behaviour and PA with mental health problems and serum testosterone and cortisol levels.Results The rates of depression,anxiety,and stress symptoms were 6.70%,12.71%,and 6.70%among 582 male college students,respectively.Compare to sedentary behavior<6 participants,participants in the sedentary behaviour>10 hours group had higher risk of depression symptoms(OR=6.66,95%CI:2.16-20.49,P=0.001)and lower testosterone levels(-13.22%,95%CI:-19.56%--6.37%,P<0.001).Participants in the PA Q4 group had lower risk of depression symptoms(OR=0.34,95%CI:0.13-0.87,P=0.025)and higher testosterone levels(8.02%,95%CI:1.37%-15.10%,P=0.017)than participants in the PA Q1 group.Further analyses found that there were no associations of sedentary behaviour with depression,anxiety and stress symptoms,testosterone and cortisol levels and testosterone/cortisol ratio among college students with high PA level(all P>0.05).Conclusions Sedentary behavior is a risk factor of depression symptoms and decreased testosterone level in college students.PA is a protective factor of depression symptoms and associated with increased testosterone levels.PA may protect the adverse effects induced by sedentary behaviour.

关 键 词：久坐 体育运动 心理健康 睾酮 

分 类 号：R818[医药卫生—放射医学] R395.6[医药卫生—临床医学]