吸入麻醉药的肺保护作用研究进展  

Research Progress of Lung-protective Effects of Inhalation Anesthetics

作　　者：关露露 王玲 GUAN Lulu;WANG Ling(Department of Anesthesiology,the First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology,Luoyang 471003,China;Department of Anesthesiology,the 989th Hospital of the PLA Joint Support Force,Luoyang 471003,China)

机构地区：[1]河南科技大学临床医学院,河南科技大学第一附属医院麻醉科,河南洛阳471003 [2]联勤保障部队第九八九医院麻醉科,河南洛阳471003

出　　处：《医学综述》2024年第13期1619-1625,共7页Medical Recapitulate

基　　金：洛阳市医疗卫生领域指导性科技计划项目(2010001A)。

摘　　要：急性肺损伤是外科手术后常见的并发症,其高发病率和死亡率促使人们不断探索预防和治疗措施。肺损伤是多种机制相互交叉、相互影响的结果,其中,最严重的肺损伤为急性呼吸窘迫综合征。近年来,吸入麻醉药的临床应用日益广泛,其在手术过程中不仅可以起到镇痛、镇静的作用,还可以对心、脑、肺、肾、肝等重要脏器起到一定的保护作用,为手术过程中的器官保护提供了新的思路和方法。目前,最常用的吸入麻醉药为七氟烷、异氟烷、地氟烷。深入探索吸入麻醉药的肺保护机制,将为临床实践和未来的研究提供理论依据。Acute lung injury is a common complication after surgery,and its high morbidity and mortality have prompted the search for preventive and curative measures.Lung injury is the result of multiple mechanisms intersecting and influencing each other,among which acute respiratory distress syndrome is the most serious lung injury.In recent years,inhalation anesthetics have been widely used in clinic,which can not only play a role in analgesia and sedation during surgery,but also play a certain role in protecting the heart,brain,lung,kidney,liver and other important organs,providing a new idea and method for organ protection during surgery.At present,the most commonly used inhalation anesthetics are sevoflurane,isoflurane,and desflurane.Exploring the lung protection mechanism of inhaled anesthetics in depth will provide theoretical basis for the clinical practice and future research.

关 键 词：急性肺损伤 急性呼吸窘迫综合征 吸入麻醉药 肺保护作用 

分 类 号：R614[医药卫生—麻醉学]