以腹泻为首发表现的C群沙门菌侵袭性肝脓肿1例及文献复习  

A Case of Salmonella Group C Invasive Liver Abscess with Diarrhea as the Initial Manifestation and Literature Review

作　　者：胡爱玲 于小杰[1] 王晓俊 杜雅丽 王娜[1] HU Ai-ling;YU Xiao-jie;WANG Xiao-jun;DU Ya-li;WANG Na(First Hospital of Qinhuangdao,Qinhuangdao 066000,China;Qinghuangdao Workers′Hospital,Qinhuangdao 066000,China)

机构地区：[1]秦皇岛市第一医院药学部,河北秦皇岛066000 [2]秦皇岛市工人医院药学部,河北秦皇岛066000

出　　处：《海峡药学》2024年第5期72-76,共5页Strait Pharmaceutical Journal

基　　金：秦皇岛市科学技术研究与发展计划项目(202301A024)。

摘　　要：目的探讨C群沙门菌侵袭性肝脓肿的临床特点与诊断、治疗要点。方法回顾性分析1例以腹泻为首发表现的C群沙门菌侵袭性肝脓肿患者的临床资料,并对相关文献进行复习。结果本例患者,男,52岁,急性起病无明确诱因出现腹泻,伴发热。便培养、引流液培养、血培养均为C群沙门菌。确诊为侵袭性肝脓肿。经皮肝穿引流后联合美罗培南抗感染治疗后体温恢复正常,炎症指标较前明显下降。结论侵袭性C群沙门菌肝脓肿临床较为少见,因以腹泻为首发表现容易误诊、延误治疗时机,规范治疗后可获得良好效果。OBJECTIVE To explore the clinical characteristics,diagnosis,and treatment of invasive liver abscess caused by Salmonella group C.METHODS A retrospective analysis was conducted on the clinical data of a patient with Salmonella C invasive liver abscess with diarrhea as the initial manifestation,and relevant literature was reviewed.RESULTS A 52-year-old man,had acute onset without clear cause of diarrhea and accompanied by fever.The stool,drainage fluid,and blood culture were all Salmonella group C.confirmed as invasive liver abscess.After percutaneous transhepatic drainage combined with meropenem anti infection treatment,the body temperature returned to normal,and the inflammatory indicators decreased significantly.CONCLUSION Invasive Salmonella C liver abscess is relatively rare in clinical practice,with diarrhea as the initial manifestation is prone to misdiagnosis and delayed treatment.Standardized treatment can achieve good results.

关 键 词：C群沙门菌 肝脓肿 抗感染治疗 

分 类 号：R969.4[医药卫生—药理学]