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作 者:江南[1] 唐晓敏 雷宇宸 赵春艳[1] JIANG Nan;TANG Xiaomin;LEI Yuchen;ZHAO Chunyan(Tongzhou District Center for Disease Control and Prevention,Beijing 101100,China)
机构地区:[1]北京市通州区疾病预防控制中心,北京101100
出 处:《实用预防医学》2024年第5期543-546,共4页Practical Preventive Medicine
基 金:北京市高层次公共卫生技术人才建设项目培养计划(学科骨干-01-043)。
摘 要:目的 了解北京市通州区农村成年居民维生素D营养状况及影响因素。方法 采用分层整群抽样方法,随机抽取北京市通州区3所乡镇共6个行政村常住居民开展问卷调查、体格检查和静脉血液样本采集工作,采用高效液相色谱-串联质谱法测定居民血清25-(OH)D含量,评估维生素D营养状况,采用多元有序logistic回归模型探索维生素D不足或缺乏影响因素。结果 最终完成调查居民共534人,居民血清25-(OH)D总体成正偏态分布,中位数16.60(12.70,22.03)ng/ml。农村居民维生素D不足率和缺乏率分别为48.50%(259/534)和18.91%(101/534);多因素回归分析显示,具有女性(OR=2.413,95%CI:1.725~3.380)、18~44岁年龄段(OR=1.842,95%CI:1.090~3.114)、超重(OR=1.605,95%CI:1.013~2.545)和肥胖(OR=1.696,95%CI:1.017~2.824)等特征的农村成年居民维生素D营养不足或缺乏的风险更高。结论 北京市通州区农村成年居民维生素D营养状况不容乐观,应重点关注农村女性、中青年、超重肥胖群体的维生素D不足和缺乏。Objective To investigate the nutritional status of vitamin D and its affecting factors amongst rural adult residents in Tongzhou District,Beijing.Methods A stratified cluster sampling method was used to randomly select permanent residents from 6 administrative villages in 3 townships of Tongzhou District for conducting a questionnaire survey,physical examination and venous blood sample collection.The residents’serum 25-hydroxyvitamin D(25-(OH)D)concentration was determined by high performance liquid chromatography(HPLC)-tandem mass spectrometry,and their nutritional status of vitamin D was evaluated.Multivariate ordered logistic regression model was employed to explore the factors influencing vitamin D insufficiency or deficiency.Results A total of 534 residents completed the survey.The residents’serum 25-(OH)D showed a positively skewed distribution,with a median of 16.60(12.70,22.03)ng/ml.The prevalence rates of vitamin D insufficiency and deficiency were 48.50%(259/534)and 18.91%(101/534)respectively.Multivariate regression analysis displayed that rural female adultresidents(OR=2.413,95%CI:1.725-3.380),residents aged 18-44 years(OR=1.842,95%CI:1.090-3.114),and adult residents with overweight(OR=1.605,95%CI:1.013-2.545)and obesity(OR=1.696,95%CI:1.017-2.824)were at higher risk of vitamin D insufficiency or deficiency.Conclusion The nutritional status of vitamin D among rural adult residents in Tongzhou District is not optimistic.Special attention should be paid to vitamin D insufficiency and deficiency in rural women and young,middle-aged,overweight and obese groups.
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