高效液相色谱法测定复合助剂中抗氧剂405含量  

Determination of Contents of Antioxidant 405 in Compound Additives by High-performance Liquid Chromatography(HPLC)

作　　者：井玉龙 郭建兰 刘明月 杜树雷 Jing Yulong;Guo Jianlan;Liu Mingyue;Du Shulei(Sanfeng Chemical Co.,Ltd.,Linyi,Shandong 276034,China)

机构地区：[1]山东省临沂市三丰化工有限公司,山东临沂276034

出　　处：《塑料助剂》2024年第1期19-21,共3页Plastics Additives

摘　　要：建立一种高效液相色谱法测定复合助剂中抗氧剂405含量。方法采用AgilentODS-C18色谱柱(4.6 mm×150 mm,5μm);以甲醇作为流动相,流速为1.2 mL/min,柱温40℃;检测波长为250 nm;进样体积为5μL。结果表明,抗氧剂405在0.3~2.4 mg/mL浓度范围内线性关系良好,相关系数r为1.0000。抗氧剂405不同浓度回收率在100%~101%之间。该方法结果准确,操作简单,重现性好,可用于复合助剂中抗氧剂405含量的准确定量。A method was established to determine the antioxidant 405 contents in compound additives by using high-performance liquid chromatography(HPLC).AgilentODS-C18(4.6 mm×150 mm,5μm)was adopted with the mobile phase of methanol at a flow rate of 1.2 mL/min.The column temperature was at 40℃.The detection wavelengths was at 250 nm.The injection volume was 5μL.Results showed that the method had a good linear relationship within the range of 0.3~2.4 mg/mL for antioxidant 405,with the correlation coefficient r of 1.0000.The recovery rates of antioxidant 405 samples were 100%~101%with different concentrations.This method is accurate,convenient and rapid so as to be used for determining the antioxidant 405 contents in compound additives.

关 键 词：高效液相色谱法 复合助剂 抗氧剂405 定量分析 

分 类 号：O657.72[理学—分析化学] TQ314.24[理学—化学]