出 处:《四川中医》2024年第4期108-113,共6页Journal of Sichuan of Traditional Chinese Medicine
基 金:四川省中医药管理局2022年度川派中医药学术传承和古籍文献整理研究项目(编号:2022CP7511)。
摘 要:目的:研究膝骨关节炎五种中医证候程度与膝关节Kellgren-Lawrence的X线分级、磁共振Recht分级的相关性。方法:选取160例膝骨关节炎不同证候患者的中医证候评分量表量化证候程度,膝关节Kellgren-Lawrence的X线分级,软骨退变的磁共振成像(magnetic resonance imaging, MRI)Recht分级并统计分析各组间的相关性。结果:将膝骨关节炎五种中医证候患者的中医证候评分量表量化证候程度与膝关节Kellgren-Lawrence的X线分级、MRI下软骨退变的Recht分级绘制散点图。五种中医证候程度与膝关节Kellgren-Lawrence的X线分级的相关性分析:肝肾亏虚型(r=0.895,P<0.01),痰瘀互结型(r=0.545,P<0.05),气血两虚型(r=0.748,P<0.01,)两者相关性具有统计学意义。五种中医证候程度与MRI下软骨退变的Recht分级的相关性分析:肝肾亏虚型(r=0.839,P<0.01),痰瘀互结型(r=0.572,P<0.01),气血两虚型(r=0.898,P<0.01)两者相关性具有统计学意义。结论:膝骨关节炎不同证候患者膝关节Kellgren-Lawrence的X线分级,软骨退变的磁共振成像(magnetic resonance imaging, MRI) Recht分级呈现不同相关程度,其中肝肾亏虚、痰瘀互结、气血两虚型患者的证候程度能反映的膝关节Kellgren-Lawrence的X线分级、MRI下软骨损伤的分级的严重程度,通过研究我们可以发现,中医的辨证分型和西医的影像学分级在某些方面存在一定的相关性,这可能意味着中医和西医在治疗膝骨关节炎方面有共同的目标和策略。Objective:To study the correlation between the degree of five traditional Chinese medicine syndromes of knee osteoarthritis and the X-ray grading and magnetic resonance Recht grading of Kellgren Lawrence in the knee joint.Method:160patients with different syndromes of knee osteoarthritis were selected to use the Traditional Chinese Medicine Syndrome Scoring Scale to quantify the degree of symptoms,Kellgren Lawrence X-ray grading of the knee joint,magnetic resonance imaging(MRI)Recht grading of cartilage degeneration,and the correlation between each group was statistically analyzed.Result:The TCM syndrome scoring scale for five types of knee osteoarthritis patients was used to quantify the degree of syndrome and plot a scatter plot with the X-ray grading of Kellgren Lawrence and the Recht grading of cartilage degeneration under MRI.The correlation analysis between the degree of five traditional Chinese medicine syndromesand the X-ray grading of Kellgren Lawrence in the knee joint:liver and kidney deficiency type(r=0.895,P<0.01),phlegm and blood stasis accumulation type(r=0.545,P<0.05),and qi and blood deficiency type(r=0.748,P<0.01)have statistical significance.The correlation analysis between the degree of five traditional Chinese medicine syndromes and the Recht grading of cartilage degeneration under MRI:liver and kidney deficiency type(r=0.839,P<0.01),phlegm and blood stasis accumulation type(r=0.572,P<0.01),and qi and blood deficiency type(r=0.898,P<0.01),the correlation between the two is statistically significant.Conclusion:The X-ray grading of Kellgren Lawrence in the knee joint and the Magnetic Resonance Imaging(MRI)Recht grading of cartilage degeneration in patients with different syndromes of knee osteoarthritis present varying degrees of correlation.Among them,the degree of symptoms in patients with liver and kidney deficiency,phlegm and blood stasis,and qi and blood deficiency can reflect the severity of Kellgren Lawrence's X-ray grading and MRI grading of cartilage damage in the knee joint.Through re
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