非营养性吸吮联合枯草杆菌二联活菌在治疗新生儿窒息后胃肠功能损伤的临床研究  

Clinical Effect of Non Nutritive Sucking Combined with Bacillus Subtilis in the Treatment of Gastrointestinal Function Damage after Neonatal Asphyxia

作　　者：林佳佳 洪珊蝶 杨敏 Lin Jiajia(Department of Neonatology,Chaozhou People’s Hospital,Chaozhou Guangdong 521021)

机构地区：[1]潮州市人民医院新生儿科,广东潮州521021

出　　处：《黑龙江医药》2024年第3期522-525,共4页Heilongjiang Medicine journal

基　　金：潮州市卫生健康局科研项目(编号:潮卫科研2021026)。

摘　　要：目的:分析非营养性吸吮联合枯草杆菌二联活菌在治疗新生儿窒息后胃肠道功能损伤的临床效果。方法:抽取2021年3月—2023年9月于本院住院的窒息后胃肠道损伤新生儿共计60例。随机数字表法分设组别,吸吮组(非营养性吸吮,n=30);联合组(n=30,非营养性吸吮+枯草杆菌二联活菌)。比较两组治疗效果。结果:详细分析了两组胃肠道功能专项指标转归情况,反馈联合组症状改善时间用时较吸吮组更短(P<0.05)。进一步分析了两组生理性体重下降恢复时间,反馈联合组干预后生理性体重下降恢复时间更短(P<0.05)。深入分析了两组临床疗效,反馈联合组临床疗效较吸吮组佳(P<0.05)。两组干预前,胃肠道菌群数量差异不大,干预后联合组菌群数量高于干预前(P<0.05),但吸吮组与干预前比较差异不大(P>0.05)。结论:针对窒息后胃肠道损伤新生儿,采用非营养性吸吮联合枯草杆菌二联活菌干预,利于患者损伤的胃肠道功能恢复,促进临床症状转归,提升干预效果,可推广。Objective:To analyze the clinical effect of non nutritive sucking combined with Bacillus subtilis in neonates with gastrointestinal dysfunction after asphyxia.Methods:A total of 60 newborns with gastrointestinal injuries after asphyxia admitted to our hospital from March 2021 to September 2023 were selected.Divide into groups using the random number table method,suction group(non nutritive suction,n=30);Joint group(n=30,non nutritive sucking+Bacillus subtilis dual live bacteria).Compare the therapeutic effects of two groups.Results:The specific indicators of gastrointestinal function in the two groups were analyzed in detail.The time for symptom improvement in the feedback combined group was shorter than that in the sucking group(P<0.05).The recovery time of physiological weight loss in the two groups was further analyzed,and the recovery time of physiological weight loss in the feedback combined group was shorter after the intervention(P<0.05).The clinical efficacy of the two groups was analyzed,and the clinical efficacy of the feedback combined group was better than that of the sucking group(P<0.05).Before intervention,there was no significant difference in the number of gastrointestinal flora between the two groups.After intervention,the number of flora in the combined group was higher than that before intervention(P<0.05),but there was no significant difference in the sucking group compared with that before intervention(P>0.05).Conclusion:For newborns with gastrointestinal injury after asphyxia,the use of non nutritive sucking combined with Bacillus subtilis dual live bacteria intervention is beneficial for the recovery of gastrointestinal function in patients with injury,promotes clinical symptom recovery,and improves intervention effectiveness,which can be promoted.

关 键 词：窒息 胃肠道损伤 枯草杆菌二联活菌 症状消失时间 非营养性吸吮 

分 类 号：R722.1[医药卫生—儿科] R725.7[医药卫生—临床医学]