辅以健脾肾助长方治疗对小儿特发性矮小症临床疗效及预后的影响  

Clinical Efficacy and Prognosis of Pediatric Idiopathic Short Stature Treated with the Combination of Strengthening the Spleen and Kidney and Assisting the Rectangular Shape

作　　者：刘春红 杜来英 唐丽萍[1] Liu Chunhong(Pediatrics Department of Anyuan County People’s Hospital,Anyuan Jiangxi 342100)

机构地区：[1]安远县人民医院儿科,江西安远342100

出　　处：《黑龙江医药》2024年第3期535-537,共3页Heilongjiang Medicine journal

基　　金：赣州市指导性科技计划项目(编号:GZ2023ZSF390)。

摘　　要：目的:分析健脾肾助长方对小儿特发性矮小症(ISS)的影响。方法:选取2020年10月—2022年10月本院收治的72例ISS患儿,按随机数字表法分为两组,各36例。对照组行重组人生长激素治疗,观察组加以健脾肾助长方治疗,持续用药12个月。对比两组临床疗效、中医证候评分、人体参数指标、糖代谢指标、不良反应。结果:观察组治疗总有效率为95.12%(39/41),高于对照组的78.05%(32/41);且治疗后的各中医证候评分低于对照组,身高为(118.94±6.36)cm,高于对照组的(115.39±5.27)cm,体重为(27.95±2.98)kg,重于对照组的(25.17±2.49)kg,生长速率为(9.98±1.25)cm/年,快于对照组的(6.68±1.01)cm/年(P<0.05);治疗前后,两组骨龄、FBG、INS相当(P>0.05);两组治疗期间均无不良反应发生。结论:健脾肾助长方能够减轻ISS患儿症状,可促进生长,且对糖代谢无明显影响,临床可推广应用。Objective:To analyze the effect of invigorating the spleen and kidney on children with idiopathic short stature(ISS).Methods:72 children with ISS admitted to our hospital from October 2020 to October 2022 were selected and divided into two groups using a random number table method,with 36 cases in each group.The control group received treatment with recombinant human growth hormone,while the observation group received treatment with invigorating spleen and kidney and assisting rectangles,with continuous medication for 12 months.Compare the clinical efficacy,traditional Chinese medicine syndrome scores,human body parameter indicators,glucose metabolism indicators,and adverse reactions between two groups.Results:The total effective rate of the observation group was 95.12%(39/41),which was higher than 78.05%(32/41)of the control group;After treatment,the scores of various traditional Chinese medicine syndromes were lower than the control group,The height was(118.94±6.36)cm,higher than the control group’s(115.39±5.27)cm,and the weight was(27.95±2.98)kg,heavier than the control group’s(25.17±2.49)kg,The growth rate was(9.98±1.25)cm/year,which was faster than the control group’s(6.68±1.01)cm/year(P<0.05);Before and after treatment,the bone age,FBG,and INS of the two groups were comparable(P>0.05);No adverse reactions occurred during the treatment of both groups.Conclusion:Strengthening the spleen and kidney can alleviate symptoms in children with ISS,promote growth,and have no significant impact on glucose metabolism.It can be widely applied in clinical practice.

关 键 词：特发性矮小症 健脾肾助长方 中医证候 不良反应 糖代谢 

分 类 号：R584[医药卫生—内分泌]