超声检查SA/TA及卵巢间质血流动力学指标联合AMH在多囊卵巢综合征诊疗中的应用分析  

Application Analysis of Ultrasonography SATA and Ovarian Interstitial Hemodynamic Indexes Combined with AMH in the Diagnosis and Treatment of Polycystic Ovarian Syndrome

作　　者：李湛 敬宗玉 胡志刚[1] Li Zhan(Department of ultrasound medicine,Shenzhen Longgang District Maternal and Child Health Hospital,Shenzhen Guangdong 518100)

机构地区：[1]深圳市龙岗区妇幼保健院超声医学科,广东深圳518100

出　　处：《黑龙江医药》2024年第3期541-544,共4页Heilongjiang Medicine journal

基　　金：深圳市龙岗区经济与科技发展专项资金医疗卫生科技计划项目(编号:LGKCYLWS2020108)。

摘　　要：目的:研究超声检查卵巢间质面积/卵巢总面积比(SA/TA)及卵巢间质血流动力学指标联合抗苗勒管激素(AMH)在多囊卵巢综合征(PCOS)诊疗中的应用。方法:选取本院2020年8月至2022年1月临床诊断的PCOS患者50例作为PCOS组,单纯多囊性卵巢(PCO)患者50例作为PCO组,以及正常女性50例作为对照组。对所有受试者均开展超声检查,对比三组SA/TA及卵巢间质血流动力学指标水平,血清AMH及生化指标水平,以Pearson相关性分析明确各项指标相关性。通过受试者工作特征曲线(ROC)分析明确SA/TA及卵巢间质血流动力学指标水平与实验室生化指标的相关性。结果:PCOS组及PCO组SA/TA、PSV、EDV水平均高于对照组,PCOS组上述指标水平均高于PCO组;PCOS组及PCO组PI、RI均低于对照组,且PCOS组PI、RI均低于PCO组(均P<0.05)。PCOS组、PCO组FPG、TG、FINS以及血清AMH水平均高于对照组,且PCOS组高于PCO组(均P<0.05)。经Pearson相关性分析发现:SA/TA、PSV、EDV水平与FPG、TG、FINS、血清AMH水平均呈正相关,而PI、RI与FPG、TG、FINS、血清AMH水平均呈负相关(均P<0.05)。经ROC曲线分析发现,SA/TA及卵巢间质血流动力学指标与血清AMH水平联合诊断PCOS的效能优于上述指标单独检测(均P<0.05)。结论:超声检查SA/TA及卵巢间质血流动力学指标联合AMH在PCOS诊疗中的应用效果较好。Objective:To analyze the application of ultrasound examination of ovarian interstitial area/total ovarian area ratio(SA/TA)and ovarian interstitial hemodynamic indicators combined with anti-Mullerian hormone(AMH)in the diagnosis and treatment of polycystic ovarian syndrome(PCOS).Methods:Fifty patients with PCOS diagnosed in our hospital from August 2020 to January 2022 were selected as the PCOS group,50 patients with polycystic ovary(PCO)alone were selected as the PCO group,and 50 normal females were selected as the control group.The levels of SA/TA and ovarian interstitial hemodynamic indexes,serum AMH and biochemical indexes were compared among the three groups.Pearson correlation analysis was used to confirm the correlation of each index.The correlation between SA/TA and ovarian interstitial hemodynamic indexes and laboratory biochemical indexes was determined by receiver operating characteristic curve(ROC)analysis.Results:The levels of SA/TA,PSV and EDV in PCOS group and PCO group were higher than control group,and the levels of above indexes in PCOS group were higher than PCO group.PI and RI in PCOS group and PCO group were lower than control group,and PI and RI in PCOS group were lower than PCO group(all P<0.05).The levels of FPG,TG,FINS and serum AMH in PCOS and PCO groups were higher than control group,and those in PCOS group were higher than PCO group(all P<0.05).Pearson correlation analysis showed that the levels of SA/TA,PSV and EDV were positively correlated with the levels of FPG,TG,FINS and serum AMH,while PI and RI were negatively correlated with the levels of FPG,TG,FINS and serum AMH(all P<0.05).ROC curve analysis showed that the combination of SA/TA and ovarian interstitial hemodynamic indexes and serum AMH level in the diagnosis of PCOS was better than the above indexes alone(all P<0.05).Conclusion:Ultrasound examination of SA/TA and ovarian interstitial hemodynamic indicators combined with AMH in the diagnosis and treatment of PCOS is better.

关 键 词：多囊卵巢综合征 超声检查 血流动力学 卵巢间质 抗苗勒管激素 

分 类 号：R711.75[医药卫生—妇产科学] R445.1[医药卫生—临床医学]