Translation and cross-cultural adaptation of the Kidney Transplant Questionnaire 25 to Greek  

作　　者：Vasileios Koutlas Eirini Tzalavra Vasileios Tatsis Charalampos Pappas Stavroula Vovlianou Stefanos Bellos Anila Duni Eleni Stamellou Konstantinos I Tsamis Michail Mitsis Evangelia Dounousi 

机构地区：[1]Department of Surgery and Kidney Transplant Unit,University Hospital of Ioannina,Ioannina 45500,Epirus,Greece [2]Department of Surgery,Faculty of Medicine,School of Health Sciences,University of Ioannina,Ioannina 45110,Epirus,Greece [3]Department of Nephrology,University Hospital of Ioannina,Ioannina 45500,Epirus,Greece [4]Department of Nephrology,General Hospital of Kavala,Kavala 65500,Greece [5]Department of Physiology,Faculty of Medicine,School of Health Sciences,University of Ioannina,Ioannina 45110,Epirus,Greece [6]Department of Nephrology,Faculty of Medicine,School of Health Sciences,University of Ioannina,Ioannina 45110,Epirus,Greece

出　　处：《World Journal of Transplantation》2024年第2期148-154,共7页世界移植杂志

摘　　要：BACKGROUND Kidney transplantation leads to continuous improvement in the survival rates of kidney transplant recipients(KTRs)and has been established as the treatment of choice for patients with end-stage kidney disease.Health-related quality of life(HRQoL)has become an important outcome measure.It is highly important to develop reliable methods to evaluate HRQoL with disease-specific questionnaires.AIM To translate the disease-specific instrument Kidney Transplant Questionnaire 25(KTQ-25)to the Greek language and perform a cross-cultural adaptation.METHODS The translation and adaptation of the original English version of the KTQ-25 to the Greek language were performed based on the International Quality of Life RESULTS Eighty-four KTRs(59 males;mean age 53.5±10.7 years;mean estimated glomerular filtration rate 47.7±15.1 mL/min/1.73 m2;mean transplant vintage 100.5±83.2 months)completed the Greek version of the KTQ-25 and the 36-item Short-Form Health Survey,and the results were used to evaluate the reliability of the Greek KTQ-25.The Cronbach alpha coefficients for all the KTQ-25 dimensions were satisfactory(physical symptoms=0.639,fatigue=0.856,uncertainty/fear=0.661,appearance=0.593,emotions=0.718,total score=0.708).The statistically significant correlation coefficients among the KTQ-25 dimensions ranged from 0.226 to 0.644.The correlation coeffi-cients of the KTQ-25 dimensions with the SF-36 physical component summary(PCS)ranged from 0.196 to 0.550;the correlation coefficients of the KTQ-25 with the SF-36 mental component summary(MCS)ranged from 0.260 to 0.655;and the correlation coefficients of the KTQ-25 with the total scores with the SF-36 PCS and MCS were 0.455 and 0.613,respectively.CONCLUSION According to the findings,the Greek version of the KTQ-25 is valid and reliable for administration among kidney transplant patients in Greece.

关 键 词：Kidney Transplant Questionnaire 25 Kidney transplantation Kidney transplant recipients Health-related quality of life Quality of life 

分 类 号：R617[医药卫生—外科学]