基于文献计量学的金莲花研究现状及热点分析  

Research status and hot spot analysis of Trollius chinensis based on bibliometrics

作　　者：高婧 陈海红 王志轩 刘杰 GAO Jing;CHEN Haihong;WANG Zhixuan;LIU Jie(Chengde Food and Drug inspection and Testing Center,Chengde 067000,China;Gansu Agricultural Reclamation Medical Alkaloids Factory,Langzhou 730300,China)

机构地区：[1]承德市食品药品检验检测中心,河北承德067000 [2]甘肃农垦药物碱厂有限公司,甘肃兰州730300

出　　处：《药物评价研究》2024年第4期862-872,共11页Drug Evaluation Research

基　　金：承德市科技计划项目(202305B007)。

摘　　要：目的总结近20年的金莲花Trollius chinensis Bunge研究现状及热点,分析其研究热点与未来趋势。方法分别检索2003年1月1日—2023年12月1日中国学术期刊全文数据库(CNKI)、万方数据库(Wanfang Data)、维普中文科技期刊数据库(VIP)、中国生物医学文献服务系统(SinoMed)、Embase、PubMed以及Web of Science(WOS)7个学术平台收录的学术期刊检索金莲花相关文献,用Endnote X8进行数据整合、去重,用VOS viewer 1.6.18软件进行文献计量和可视化分析。结果金莲花近20年来中英文文献发表量均呈波动上升趋势,总体数量方面中文文献远高于英文文献;关键词聚类分析显示主要研究内容以活性成分与药理作用为主,其次是质量评价与制剂临床应用。结论金莲花研究内容在分子层面的作用机制和药动学方面较少,具有完善与深入挖掘的必要性。Objective In order to understand the research status and hot spots of Trollius chinensis in the past 20 years,and to analyze its future research trends.Methods The CNKI,Wanfang Data,VIP,SinoMed,Embase,PubMed and Web of Science(WOS)were searched from January 1,2003 to December 31,2022,respectively,and the literature related to Trollius chinensis were integrated and deduplicated using Endnote X8,and bibliometric and visual analysis were conducted using VOS viewer 1.6.18 software.Results The publication volume of Chinese literature and English literature in Trollius chinensis has shown a fluctuating upward trend in recent 20 years.In terms of overall quantity,Chinese literature significantly outweighs English literature.The keyword clustering analysis indicates that the primary research focus is on active ingredients and pharmacological effects,followed by quality evaluation and clinical application of formulations.Conclusion There are more Chinese literature than English literature.Keyword clustering shows that the main research content of Trollius chinensis currently focuses on the study of active components and pharmacological effects,followed by quality evaluation and preparation and clinical application.In future research,more consideration should be given to the molecular mechanism of action and pharmacokinetics research of Trollius chinensis Bunge.

关 键 词：金莲花 短瓣金莲花 文献计量学 活性成分 药理作用 质量评价 

分 类 号：R282.7[医药卫生—中药学]