从昼夜节律角度浅析荨麻疹发病时间规律  

Analysis of urticaria onset time from the perspective of circadian rhythm

作　　者：鄢德政 张红星 王钏 韩永丽 李钰 YAN Dezheng;ZHANG Hongxing;WANG Chuan;HAN Yongli;LI Yu(Rehabilitation Department,Hubei Provincial Government Hospital,Wuhan,Hubei 430061,China;College of Acupuncture and Moxibustion and Orthopaedics,Hubei University of Traditional Chinese Medicine,Wuhan,Hubei 430061,China;Acupuncture and Moxibustion Department,Wuhan First Hospital,Wuhan,Hubei 430000,China;Acupuncture and Moxibustion Department,The First Affiliated Hospital of He´nan University of Traditional Chinese Medicine,Zhengzhou,He´nan 450000,China;Massage Department,Xianning Traditional Chinese Medicine Hospital,Xianning,Hubei 437100,China)

机构地区：[1]湖北省直属机关医院康复科,湖北武汉430061 [2]湖北中医药大学针灸骨伤学院,湖北武汉430061 [3]武汉市第一医院针灸科,湖北武汉430000 [4]河南中医药大学第一附属医院针灸科,河南郑州450000 [5]咸宁市中医医院推拿科,湖北咸宁437100

出　　处：《安徽医药》2024年第7期1472-1475,共4页Anhui Medical and Pharmaceutical Journal

基　　金：“十三五”国家重点研发计划“中医药现代化研究”重点项目(2017YFC1703605)。

摘　　要：荨麻疹是一种临床上常见的皮肤疾病,已有的流行病学发现荨麻疹的发病时间存在一定的规律,其多表现为日间症状缓解,于夜间发作或加重,与《黄帝内经》中“旦慧、昼安、夕加、夜甚”所体现的昼夜节律基本相符合,而现代研究中的生物钟理论也反应出人体免疫机制与疾病的进展同样存在昼夜变化,故从传统中医和现代研究角度探究和分析荨麻疹这一发病规律形成的原因和机制,以期更全面认识荨麻疹的疾病病机,为荨麻疹的临床诊疗思路提供参考和启发。Urticaria is a common skin disease in clinic.The existing epidemiological studies on the timing of urticaria attacks have found a certain circadian rhythm that most of the symptoms were relieved during the day and aggravated at night,which is in line with the statement of the theory of timing rule of the onset and transformation of disease in the Inner Canon of Yellow Emperor(Huangdi Neijing).The biological clock theory in modern research also reflects that the body´s immune mechanisms and the progression of disease also vary between day and night.Now from the perspective of traditional Chinese medicine and modern research,this paper explores and analyzes the causes and mechanisms of urticaria,in order to provide reference and inspiration for a comprehensive understanding of the disease mechanism of urticaria and clinical Chinese medical treatment ideas of urticaria.

关 键 词：荨麻疹 医学 中国传统 发病时间 昼夜节律 发病规律 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]