短期经鼻高流量加温加湿氧疗与无创呼吸机辅助通气在呼吸衰竭患者中的运用效果对比  

Comparison of the Effects of Short-term High-flow Heated and Humidified Oxygen Therapy via Nasal Catheter and Non-invasive Ventilator-assisted Ventilation in Patients with Respiratory Failure

作　　者：庄三妹 余晓红 张宇鹏[1] ZHUANG Sanmei;YU Xiaohong;ZHANG Yupeng(Department of Respiratory and Critical Care Medicine,Jinjiang Hospital(Shanghai Sixth People's Hospital Fujian Hospital),Quanzhou,Fujian Province,362200 China)

机构地区：[1]晋江市医院(上海市第六人民医院福建医院)呼吸与危重症医学科,福建泉州362200

出　　处：《中外医疗》2024年第12期5-8,共4页China & Foreign Medical Treatment

基　　金：泉州医学高等专科学校校级课题(XYL2207)。

摘　　要：目的研究分析短期高流量经鼻导管加温加湿氧疗(High Flow Heated Humidified Oxygen Therapy Via Nasal Catheter,HFNC)与无创呼吸机辅助通气在呼吸衰竭患者中的运用效果。方法随机选取2022年6月—2023年9月晋江市医院收治的50例呼吸衰竭患者为研究对象,以不同治疗方式分为两组,各25例,对照组予以无创呼吸机辅助通气,观察组予以短期HFNC治疗,比较两组不同治疗时间段的基础体征、动脉血气以及并发症发生率。结果治疗后,观察组心率、呼吸频率及平均动脉压均优于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组血氧分压值、血二氧化碳分压值与血氧饱和度值均优于对照组,差异有统计学意义(P均<0.05)。观察组并发症发生率(8.00%)低于对照组(32.00%),差异有统计学意义(χ^(2)=4.500,P=0.033)。结论短期HFNC用于呼吸衰竭患者的辅治,较无创呼吸机辅助通气更有助于改善患者的基础体征及动脉血气,减少并发症发生。Objective To study and analysis the effect of short-term high-flow heated and humidified oxygen therapy via nasal catheter(HFNC)and non-invasive ventilator-assisted ventilation in patients with respiratory failure.Methods Fifty patients with respiratory failure admitted to Jinjiang City Hospital from June 2022 to September 2023 were randomly selected as the study objects,and divided into two groups with 25 cases each by different treatment methods.The control group was given non-invasive ventilator assisted ventilation,and the observation group was given short-term HFNC treatment.The basic signs,arterial blood gas and complication rate of the two groups were compared in different treatment periods.Results After treatment,the heart rate,respiratory rate and mean arterial pressure in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the blood oxygen partial pressure value,blood carbon dioxide partial pressure value and blood oxygen saturation value of the observation group were better than those of the control group,and the differences were statistically significant(all P<0.05).The complication rate of the observation group(8.00%)was lower than that of the control group(32.00%),and the difference was statistically significant(χ^(2)=4.500,P=0.033).Conclusion Short-term HFNC for adjuvant treatment of patients with respiratory failure is more helpful than non-invasive ventilator-assisted ventilation to improve patients'basal signs and arterial blood gases and reduce complications.

关 键 词：呼吸衰竭 短期高流量经鼻导管加温加湿氧疗 无创呼吸机 动脉血气 

分 类 号：R5[医药卫生—内科学]