血清CRP、PCT与血常规WBC检验在儿童细菌性感染疾病中的鉴别价值研究  

Study on the Differential Value of Serum CRP,PCT and Routine Blood Tests in Bacterial Infectious Diseases in Children

作　　者：单群 陈在旺 郭苗 SHAN Qun;CHEN Zaiwang;GUO Miao(Department of Laboratory,Shanxian Dongda Hospital,Heze,Shandong Province,274300 China;Department of Biochemistry,Shanxian Central Hospital,Heze,Shandong Province,274300 China)

机构地区：[1]山东省单县东大医院有限公司检验科,山东菏泽274300 [2]山东省单县中心医院生化室,山东菏泽274300

出　　处：《中外医疗》2024年第12期62-64,97,共4页China & Foreign Medical Treatment

摘　　要：目的研究血清C反应蛋白(C Reactive Protein,CRP)、降钙素原(Procalcitonin,PCT)、血常规白细胞计数(White Blood Cell Count,WBC)联合用于检验儿童细菌性感染疾病的价值。方法回顾性选取2021年1月—2023年12月山东单县东大医院诊治细菌性感染疾病43例患儿的临床资料作为观察组,回顾性选取同期于本院进行体检的健康儿童43名的临床资料作为对照组,对比两组血清CRP、PCT及血常规WBC指标检验结果,计算单一指标、三项指标联合检验的灵敏度、特异度及准确度。结果经检验,观察组感染患儿CRP、PCT及血常规WBC指标水平均明显高于对照组,差异有统计学意义(P均<0.05)。另外三项指标联合检验疾病的灵敏度95.35%、准确度94.19%均明显高于单一指标检验,差异有统计学意义(P均<0.05)。结论临床鉴别诊断儿童细菌性感染疾病可通过CRP、PCT、血常规WBC指标三项结合检验的方式,相比单一指标分析准确性更高,为后续治疗提供数据支持。Objective To study the value of serum CRP(C-reactive protein),PCT(procalcitonin),and routine WBC(white blood cell count)combined for testing bacterial infectious diseases in children.Methods The clinical data of 43 cases of children with bacterial infections diagnosed in Shanxian Dongda Hospital from January 2021 to December 2023 werere retrospectively selected as the observation group,and the clinical data of 43 healthy children who underwent physical examination in the hospital during the same period were retrospectively selected as the control group.The results of the serum CRP,PCT and blood routine WBC indexes were compared,and the sensitivity,specificity and accuracy of the single-indicator and three-indicator combined tests were calculated.Results The levels of CRP,PCT and blood routine WBC indexes of infected children in the observation group were significantly higher than those of the control group,and the differences were statistically significant(all P<0.05).The sensitivity 95.35%and the accuracy 94.19%of the three-indicator combined test of the disease were significantly higher than that of the single-indicator test,and the differences were statistically significant(both P<0.05).Conclusion Clinical differential diagnosis of children's bacterial infections can be made by combining the three tests of CRP,PCT,and routine blood WBC indexes,which is more accurate than the single-indicator analysis,and provides data support for subsequent treatment.

关 键 词：血清CRP PCT 血常规检验 儿童细菌性感染疾病 

分 类 号：R725[医药卫生—儿科]