Occupational physical activity, all-cause, cardiovascular disease, and cancer mortality in 349,248 adults: Prospective and longitudinal analyses of the MJ Cohort  

作　　者：Emmanuel Stamatakis Matthew N.Ahmadi Tiana-Lee Elphick Bo-Huei Huang Susan Paudel Armando Teixeira-Pinto Li-Jung Chen Borja del Pozo Cruz Yun-Ju Lai Andreas Holtermann Po-Wen Ku 

机构地区：[1]Sydney School of Health Sciences,Faculty of Medicine and Health,Charles Perkins Centre,University of Sydney,Sydney,NSW 2006,Australia [2]Sydney School of Public Health,Faculty of Medicine and Health,University of Sydney,Sydney,NSW 2006,Australia [3]Department of Exercise Health Science,“National”Taiwan University of Sport,Taichung 40404,China [4]Department of Sports Science and Clinical Biomechanics,University of Southern Denmark,Odense 5230,Denmark [5]Division of Endocrinology and Metabolism,Department of Internal Medicine,Puli Branch of Taichung Veterans General Hospital,Nantou 54552,China [6]National Research Centre for the Working Environment,Copenhagen 2100,Denmark [7]Graduate Institute of Sports and Health Management,“National”Chung Hsing University,Taichung 40227,China

出　　处：《Journal of Sport and Health Science》2024年第4期579-589,共11页运动与健康科学（英文）

基　　金：supported by a National Health and Medical Research Council (Australia) Investigator Grant (APP1194510)

摘　　要：Background:Evidence on the health benefits of occupational physical activity(OPA)is inconclusive.We examined the associations of baseline OPA and OPA changes with all-cause,cardiovascular disease(CVD),and cancer mortality and survival times.Methods:This study included prospective and longitudinal data from the MJ Cohort,comprising adults over 18 years recruited in 1998-2016,349,248 adults(177,314 women)with baseline OPA,of whom 105,715(52,503 women)had 2 OPA measures at 6.3±4.2 years(mean±SD)apart.Exposures were baseline OPA,OPA changes,and baseline leisure-time physical activity.Results:Over a mean mortality follow-up of 16.2±5.5 years for men and 16.4±5.4 years for women,11,696 deaths(2033 of CVD and 4631 of cancer causes)in men and 8980 deaths(1475 of CVD and 3689 of cancer causes)in women occurred.Combined moderately heavy/heavy baseline OPA was beneficially associated with all-cause mortality in men(multivariable-adjusted hazard ratio(HR)=0.93,95%confidence interval(95%CI):0.89-0.98 compared to light OPA)and women(HR=0.86,95%CI:0.79-0.93).Over a mean mortality follow-up of 12.5±4.6 years for men and 12.6±4.6 years for women,OPA decreases in men were detrimentally associated(HR=1.16,95%CI:1.01-1.33)with all-cause mortality,while OPA increases in women were beneficially(HR=0.83,95%CI:0.70-0.97)associated with the same outcome.Baseline or changes in OPA showed no associations with CVD or cancer mortality.Conclusion:Higher baseline OPA was beneficially associated with all-cause mortality risk in both men and women.Our longitudinal OPA analyses partly confirmed the prospective findings,with some discordance between sex groups.

关 键 词：Cancer Cardiovascular disease EPIDEMIOLOGY Mortality 

分 类 号：R195[医药卫生—卫生统计学] G804.2[医药卫生—卫生事业管理]