ADC值、FA值与TIA患者血管狭窄程度的相关性及其联合检测对TIA患者发生ACI的预测价值  

Correlation of ADC Value, FA Value with the Degree of Vascular Stenosis in TIA Patients and the Predictive Value of Combined Detection for the Occurrence of ACI in TIA Patients

作　　者：靳科菲 高俊[2] 刘晓伟 徐建林[3] JIN Kefei;GAO Jun;LIU Xiaowei;XU Jianlin(Department of Imaging,the Second People’s Hospital of Henan Province,Zhengzhou 457501,China;Department of Imaging,Henan Armed Police Henan Corps Hospital,Zhengzhou 450000,China;Department of Oncology and Hematology,Henan Armed Police Henan Corps Hospital,Zhengzhou 450000,China)

机构地区：[1]河南省第二人民医院影像科,河南郑州457501 [2]武警河南总队医院影像科,河南郑州450000 [3]武警河南总队医院肿瘤血液科,河南郑州450000

出　　处：《河南医学研究》2024年第11期1982-1986,共5页Henan Medical Research

摘　　要：目的 探究弥散加权成像(DWI)参数表现扩散系统(ADC)值、弥散张量成像(DTI)参数向异性分数(FA)值与短暂性脑缺血发作(TIA)血管狭窄程度的相关性,及联合检测对TIA患者发生急性脑梗死(ACI)的预测价值。方法 选取河南省第二人民医院2022年1月至2023年1月收治的110例TIA患者,均进行DWI、DTI检查。比较不同血管狭窄程度TIA患者ADC值、FA值,分析ADC值、FA值与TIA血管狭窄程度的相关性。根据TIA患者入院治疗后3个月内是否发生ACI,分为ACI组和非ACI组,分析ADC值、FA值联合检测对TIA患者发生ACI的预测价值。结果 血管狭窄程度轻度、中度、重度TIA患者ADC值、FA值比较:重度<中度<轻度(P<0.05);TIA患者ADC值、FA值与血管狭窄程度呈负相关(r=-0.786、-0.679,P<0.05);非ACI组ADC值、FA值高于ACI组(P<0.05);ADC值与FA值联合检测预测TIA患者发生ACI的AUC、敏感度均高于DC值、FA值单独检测(P<0.05)。结论 ADC值、FA值可用于评估TIA患者血管狭窄程度,且联合检测对TIA患者发生ACI具有较高的预测价值,临床常可通过DWI检查和DTI检查获取ADC值、FA值,用于评估TIA患者血管狭窄的严重程度,并预测ACI发生的可能性,为临床早期制定干预措施提供依据,进而减少ACI的发生,改善TIA患者的预后。Objective To investigate the correlation of diffusion weighted imaging(DWI)parameter apparent diffusion coefficient(ADC)value,diffusion tensor imaging(DTI)parameter fractional anisotropy(FA)value with the degree of vascular stenosis in transient ischemic attack(TIA),and the predictive value of combined detection for the occurrence of acute cerebral infarction(ACI)in TIA patients.Methods A total of 110 TIA patients admitted to the Second People’s Hospital of Henan Province from January 2022 to January 2023 were selected,and all patients underwent DWI and DTI examinations.The ADC and FA values were compared among different degrees of vascular stenosis in TIA patients,the correlation of ADC and FA values with the degree of vascular stenosis in TIA patients were analyzed.According to whether TIA patients develop ACI within 3 months after admission,they are divided into ACI group and non ACI group.The predictive value of combined detection of ADC and FA values for the occurrence of ACI in TIA patients was analyzed.Results The ADC and FA values of TIA patients with mild,moderate,and severe vascular stenosis were compared:severe<moderate<mild,with significant differences in pairwise comparison(P<0.05);the ADC and FA values of TIA patients were negatively correlated with the degree of vascular stenosis(r=-0.786,-0.679,P<0.05).The ADC and FA values in the non ACI group were significantly higher than those in the ACI group(P<0.05).The AUC and sensitivity of the combined detection of ADC value and FA value predictive value for the occurrence of ACI in TIA patients was higher than that of DC value and FA value alone(P<0.05).Conclusion ADC and FA values can be used to evaluate the degree of vascular stenosis in TIA patients,and combined detection has high predictive value for the occurrence of ACI in TIA patients.In clinical practice,ADC and FA values can be obtained through DWI and DTI examinations to evaluate the severity of vascular stenosis in TIA patients,predict the possibility of ACI occurrence,and provide a basis fo

关 键 词：弥散加权成像 参数表现扩散系统 弥散张量成像 向异性分数 短暂性脑缺血发作 急性脑梗死 

分 类 号：R445[医药卫生—影像医学与核医学]