维持性血液透析患者新型冠状病毒感染相关高凝状态及血栓并发症的发病机制综述  

Pathogenesis of coronavirus disease 2019-related hypercoagulability and thrombotic complications in patients undergoing maintenance hemodialysis

作　　者：龚俊峰 张燕[1] 罗琰琨[1] GONG Junfeng;ZHANG Yan;LUO Yankun(Department of Nephrology,the Fifth Clinical Medical College of Shanxi Medical University,Taiyuan,Shanxi,030001)

机构地区：[1]山西医科大学第五临床医学院肾内科,山西太原030001

出　　处：《实用临床医药杂志》2024年第10期136-140,共5页Journal of Clinical Medicine in Practice

基　　金：山西省科技计划项目(202103021224389)。

摘　　要：新型冠状病毒感染(COVID-19)可诱发患者凝血功能障碍,且与血栓并发症(微血管血栓形成、静脉血栓栓塞、脑卒中)风险升高相关。在维持性血液透析患者中,COVID-19相关凝血功能障碍及血栓并发症的发生风险将进一步升高。本文综述维持性血液透析患者COVID-19相关高凝状态及血栓并发症的发病机制,以期为该疾病的诊治提供参考依据。Coronavirus disease 2019(COVID-19)can induce coagulation dysfunction in patients and is associated with an increased risk of thrombotic complications,including microvascular thrombosis,venous thromboembolism,and stroke.In patients undergoing maintenance hemodialysis,the risk of COVID-19-related coagulation dysfunction and thrombotic complications is further elevated.This article reviewed the pathogenesis of COVID-19-related hypercoagulability and thrombotic complications in patients undergoing maintenance hemodialysis,aiming to provide a reference for the diagnosis and treatment of this disease.

关 键 词：维持性血液透析 新型冠状病毒感染 严重急性呼吸综合征冠状病毒2型 凝血 血栓 

分 类 号：R511[医药卫生—内科学] R692[医药卫生—临床医学] R459.5